ArticleIrish journal of medical science2026
Assessment of left ventricle strain of cardiovascular-asymptomatic patients of type 2 diabetes mellitus with preserved cardiovascular function through Dobutamine stress echocardiography.
Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCardiovascular diseases (CVD) are the primary causes of mortality in diabetic patients. Recent advances have demonstrated that stress echocardiography can assist in identifying early cardiovascular changes before the onset of symptoms.
aimThis research aims to identify early biomarkers of CVD utilizing stress echocardiography.
methodsThirty patients diagnosed with type 2 diabetes mellitus were included in this study. All individuals exhibited no symptoms related to the cardiovascular system and maintained a preserved left ventricle (LV) ejection fraction. Initially, physical examinations, electrocardiogram, and routine echocardiography were conducted for patients. Subsequently, patients underwent evaluation via stress echocardiography following the administration of dobutamine.
resultsA significant relationship was observed between FBS levels and alterations in LV GLS at the peak of the stress echocardiography test. Nonetheless, no association was identified among the demographic information of the patients, such as gender, age, and BMI. There was no significant association between HbA1c, the duration of diabetes, and insulin consumption with the LV GLS index.
conclusionA significant relationship exists between FBS levels and LV GLS. This finding highlights the usefulness of dobutamine stress echocardiography in identifying early cardiovascular changes before the onset of symptoms in diabetic patients with CVD. KEY MESSAGES: • Cardiovascular pathology in diabetes begins before symptoms presentation. • Poor glycemic control is associated with alterations in LV GLS. • Prevention of cardiovascular diseases should begin earlier than symptomatic disease.
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