Evidence map›Paper›PMID 41212485›Full record

ArticleJournal of neurovirology2025

Clinical features of varicella-zoster virus meningitis diagnosed by polymerase chain reaction without abnormal routine cerebrospinal fluid analysis.

Akihiro Kitamura, Ryutaro Nakamura, Seiji Sugiyama, Ryota Tamura, Takahito Tsukamoto, Hiroyuki Yabata, Shuhei Kobashi, Yoshitaka Tamaki, Nobuhiro Ogawa, Isamu Yamakawa and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurovirology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Akihiro KitamuraDepartment of Neurology, Clinical Neuroscience Research Unit, Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, 520-2192, Japan. yutakuto@belle.shiga-med.ac.jp.
Ryutaro NakamuraDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Seiji SugiyamaDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Ryota TamuraDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Takahito TsukamotoDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Hiroyuki YabataDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Shuhei KobashiDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Yoshitaka TamakiDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Nobuhiro OgawaDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Isamu YamakawaDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Tomoya TerashimaDepartment of Neurology, Shiga University of Medical Science, Otsu, Japan.
Makoto UrushitaniDepartment of Neurology, Clinical Neuroscience Research Unit, Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, 520-2192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the clinical features of varicella-zoster virus (VZV) meningitis cases diagnosed by polymerase chain reaction (PCR) despite normal routine cerebrospinal fluid (CSF) testing. A retrospective review was performed on hospitalized central nervous system (CNS) infection cases at our institution from 2013 to 2024. VZV meningitis cases were analyzed and divided into two groups: those diagnosed by positive PCR without routine CSF abnormalities (PCR Group) and those with routine CSF abnormalities (Usual Group). PCR methods included conventional techniques and a rapid detection system (FilmArray

Indexed as

Herpesvirus 3, HumanMeningitis, ViralVaricella Zoster Virus InfectionAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPolymerase Chain ReactionRetrospective StudiesNormal routine cerebrospinal fluid testingPolymerase chain reactionThe FilmArray® meningitis/encephalitis panelVaricella-zoster virus meningitis

Identifiers

PMID41212485
PMCPMC12701014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.