ArticleOdontology2026
Equisetum hyemale enhances local bone regeneration in murine maxillary defects: an in vivo study.
Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
We investigated a maxillary bone defect model to test a synthetic extracellular matrix (HyStem®-HP) (hyaluronan) alone or associated with BG-Carb (BG-Carb)-a bioactive glass-carbon material made of a green waste (Equisetum hyemale). BG-Carb cytocompatibility was evaluated in Dental Pulp Cells (DPC) at 24, 48, and 72 h. Animals were treated with both materials and euthanized on days 7 and 21. The inflammatory process, bone regeneration, and epithelial formation were quantified. Data were analyzed at a 95% confidence level using Student's t-test or Mann Whitney test (p < 0.05). BG-Carb did not impair dental pulp cell viability. BG-Carb also promoted increased bone formation at 7 days compared to HyStem®-HP alone. At 21 days, bone formation was similar between groups; however, less granulation tissue and greater epithelial thickness were observed in the BG-Carb-treated samples. BG-Carb showed biocompatibility promoting early bone regeneration and tissue organization during repair. BG-Carb is a promise candidate for bone regeneration.
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