ArticleWorld journal of urology2025
Tubularized bladder mucosa technique compared with Politano-Leadbetter procedures for treating primary vesicoureteral reflux in the pediatric population: a prospective cohort study.
Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTubularized bladder mucosa technique was introduced for managing recurrent vesicoureteral reflux after failed reimplantation. Its application in cases of primary vesicoureteral reflux has not previously been reported. This prospective cohort study compares the tubularized bladder mucosa technique with the established Politano-Leadbetter procedure for the treatment of primary vesicoureteral reflux.
methodsPatients with a confirmed diagnosis of primary vesicoureteral reflux who met the inclusion criteria were enrolled. They were prospectively assigned to either the tubularized bladder mucosa group or the Politano-Leadbetter group. The outcomes included vesicoureteral reflux recurrence rates at 3 months, febrile urinary tract infection incidence and postoperative development of ureterovesical junction stenosis.
resultsBetween January 2024 and January 2025, 56 children (84 ureters) with median age 38.07 months were were enrolled and assigned to either tubularized bladder mucosa (27 patients/40 ureters) or Politano-Leadbetter group (29 patients/44 ureters). The tubularized bladder mucosa group demonstrated significantly shorter operative times (108.15 ± 16.25 vs. 123.79 ± 25.67 min, p = 0.018). During the 3-month follow-up, no significant differences were observed between the two groups in terms of vesicoureteral reflux recurrence rate (p = 0.43) or febrile urinary tract infection rate (p = 0.97). No cases of ureterovesical junction stenosis occurred in either group.
conclusionsThis study demonstrates that the tubularized bladder mucosa technique is a safe and effective treatment treatment for primary vesicoureteral reflux, with excellent short-term outcomes comparable to those of conventional procedures. Its distinct advantages - including procedural simplicity, minimal tissue dissection, and shorter operative duration - position it as an ideal candidate for pneumovesicoscopic adaptation. TRIAL REGISTRATION NUMBER: ChiCTR2400081850; Date: March 15th, 2024.
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