Evidence map›Paper›PMID 41212426›Full record

SynthesisCurrent allergy and asthma reports2025

Choice of Mucosa Removal in Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Network Meta-Analysis.

Ying-Xing Wu, Ke-Zhang Zhu, Ming Zeng, Zheng Liu

Abstract readNetwork Meta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current allergy and asthma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ying-Xing Wu *Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.
Ke-Zhang Zhu *Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.
Ming ZengDepartment of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China. zmsx77@163.com.
Zheng LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China. zhengliuent@hotmail.com.

Funding

National Key Research and Development Program of China 2023YFC2507900
6 · The paper itself

Abstract

purpose of reviewThe optimal management of mucosal tissues during endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP) remains controversial. This systematic review and network meta-analysis aimed to compare the efficacy and safety between mucosa-preserving surgical techniques, such as functional endoscopic sinus surgery (FESS) and extended endoscopic sinus surgery (EESS), and radical mucosa-resecting endoscopic sinus surgery (RESS) for the treatment of CRSwNP. RECENT

findingsNine studies involving 1,224 patients were included. RESS was associated with significantly lower recurrence rates compared to both FESS (relative risk [RR]: 2.37; 95% confidence interval [CI]: 1.64, 3.43) and EESS (RR: 2.22; 95% CI: 1.48, 3.36). EESS demonstrated a significantly lower revision surgery rate than FESS (RR: 2.95; 95% CI: 1.89, 4.82). Additionally, RESS showed greater improvement in overall symptom/severity visual analogue scale (VAS, 0-10 cm) scores compared to FESS (mean difference [MD]: -2.82, 95% CI: -3.02, -2.62) and EESS (MD: -2.64, 95% CI: -4.09, -1.21). No significant differences were observed in complication rates among these surgical techniques. Besides, no statistically significant differences were found in VAS-loss of smell score, Sino Nasal Outcome Test-22 score, or Lund-Kennedy endoscopic score. Mucosal resection during endoscopic sinus surgery is associated with reduced postoperative recurrence and improved overall symptom control in patients with CRSwNP compared to mucosal preservation techniques. The safety profiles of these surgical approaches are comparable.

Indexed as

EndoscopyNasal MucosaNasal PolypsParanasal SinusesRhinosinusitisChronic DiseaseHumansTreatment OutcomeChronic rhinosinusitis with nasal polypsEndoscopic sinus surgeryMucosal removalNetwork meta-analysis

Identifiers

PMID41212426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.