Evidence map›Paper›PMID 41212304›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Elevated defeatist performance beliefs predict state increases in negative symptoms in daily life in clinical high-risk for psychosis youth: implications for mobile health treatments.

Lauren Luther, Ian M Raugh, Luca Bela G Webber, Paul M Grant, Aaron T Beck, Vijay A Mittal, Elaine Walker, Gregory P Strauss

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In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Lauren LutherDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
Ian M RaughDepartment of Psychiatry, Douglas Mental Health Institute, McGill University, Montréal, Québec, Canada.
Luca Bela G WebberDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
Paul M GrantCenter for Recovery-Oriented Cognitive Therapy, Beck Institute, Bala Cynwyd, PA, USA.
Aaron T BeckCenter for Recovery-Oriented Cognitive Therapy, Beck Institute, Bala Cynwyd, PA, USA.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL, USA.
Elaine WalkerDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.
Gregory P StraussDepartment of Psychology, University of Georgia, 125 Baldwin St, Athens, GA, 30602, USA. gstrauss@uga.edu.

Funding

Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
Mechanisms Underlying Emotion Regulation Abnormalities in Youth at Clinical High-Risk for PsychosisR21MH119438 · NIMH · UNIVERSITY OF GEORGIA · PI STRAUSS, GREGORY P · 2019 to 2020
$415k
NIMH NIH HHS R01 MH116039NIMH NIH HHS R01-MH116039NIMH NIH HHS R21 MH119438NIMH NIH HHS R21-MH119438
6 · The paper itself

Abstract

backgroundNegative symptoms are a strong predictor of conversion to a formal psychotic disorder in youth at clinical high-risk for developing psychosis (CHR). Identification of temporally precise mechanisms underlying increases in negative symptoms could enhance early intervention and specifically support the utility of mobile health treatments. Guided by Cognitive Behavioral models of psychopathology, we examine whether a core type of biased thinking-defeatist performance beliefs (DPB)-is a real-world mechanism of negative symptoms as well as a secondary symptom that is common in CHR youth: depressed mood.

methodsCHR youth (n = 119) and healthy control (CN; 59) subjects completed ecological momentary assessment surveys assessing DPB, negative symptoms, and depressed mood for six days.

resultsCHR youth reported elevated DPB in daily life compared to CN. Greater DPB were associated with greater concurrent negative symptoms and depressed mood in daily life. Time-lagged analyses demonstrated that increased DPB at time t led to elevations in negative symptoms and depressed mood at t + 1 above and beyond the effects of the respective symptom at time t; DPB also varied across time of day, study day, day of the week, activity context, and social partners.

conclusionsDPB may be a promising shared mechanism contributing to negative symptoms and depressed mood in CHR youth in their daily life. Findings also provide proof-of-concept support for the utility of mobile health treatments targeting DPB by identifying key moments where DPB fluctuate in CHR youths' everyday environments.

Indexed as

DepressionPsychotic DisordersAdolescentDigital HealthEcological Momentary AssessmentFemaleHumansMaleRiskClinical high-riskCognitive behavioral therapyEcological momentary assessmentPsychosis

Identifiers

PMID41212304
PMCPMC13526039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.