Evidence map›Paper›PMID 41212286›Full record

ArticleEuropean child & adolescent psychiatry2026

Personality functioning improvements in adolescents from an early intervention clinic for personality disorders.

Luana Palermo, Marialuisa Cavelti, Silvano Sele, Carla Sharp, Corinna Reichl, Michael Kaess

Erratum issuedAbstract read
In one paragraph

Article in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Luana PalermoUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0009-0007-0381-3962
Marialuisa CaveltiUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4726-396X
Silvano SeleUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-0767-2515
Carla SharpDepartment of Psychology, University of Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0001-8349-4701
Corinna ReichlUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-0092-2788
Michael KaessUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland. michael.kaess@upd.ch.ORCID http://orcid.org/0000-0003-0031-7764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early intervention of personality disorders (PD) in adolescents is crucial due to their long-term developmental impact. Dimensional models, like the DSM-5 Alternative Model for Personality Disorders (AMPD), may facilitate early detection and intervention, although their applicability in adolescent clinical populations is under-researched. This longitudinal study examines changes in PD diagnosis and impairments in personality functioning according to the AMPD and explores potential predictors in a clinical adolescent cohort. 227 adolescents (M age = 15.25, 85.02% female) from an outpatient clinic for early PD intervention were assessed at baseline, one year, and two years. Personality functioning was measured using the Semi-Structured Interview for Personality Functioning, psychiatric diagnoses with the Mini International Neuropsychological Interview, and psychosocial functioning with the Social and Occupational Functioning Assessment Scale. Mixed regression models were applied for analysis. The probability of a PD diagnosis significantly decreased over two years (OR = 0.54, p = .011). Significant improvements were observed in identity (β = -0.191, p < .001), self-direction (β = -0.243, p < .001), empathy (β = -0.147, p < .001) and intimacy (β = -0.136, p < .001). Age, sex, psychiatric comorbidity, psychosocial functioning at baseline, treatment setting (inpatient versus outpatient) and dose did not influence PD diagnosis remission or changes in personality functioning, but higher baseline psychosocial functioning was linked to less improvement in self-direction (β = 0.008, p = .033). Personality functioning improved over time, supporting the notion that PD pathology in adolescents is amenable to change. Further research is needed to examine individual trajectories of personality functioning and refine targeted intervention strategies.

Indexed as

Early Medical InterventionPersonalityPersonality DisordersAdolescentEarly DiagnosisFemaleHumansLongitudinal StudiesMalePsychosocial FunctioningAdolescenceEarly DetectionMixed-Regression ModelsPersonality DisorderPersonality Functioning

Identifiers

PMID41212286
PMCPMC13219104

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.