Evidence map›Paper›PMID 41212272›Full record

ArticleNeurochemical research2025

A Novel H

Yan He, Xiao Wang, Yanqi Wu, Honghao Xu, Xutao Wang, TianTian Wang, Lian Liu, Shuisheng Lei, Xiaoqin Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan HeDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Xiao WangDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Yanqi WuDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Honghao XuDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Xutao WangDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
TianTian WangDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Lian LiuSchool of Animal Science and Technology, Foshan University, Foshan, 528225, China. llian2004@163.com.
Shuisheng LeiThe Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China. leishuisheng@126.com.
Xiaoqin ZhuDepartment of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China. whzhuxiaoqin@gzhmu.edu.cn.

Funding

Natural Science Foundation of Guangdong Province of China 2023A1515011897Natural Science Foundation of Guangdong Province of China 2023A1515140070Science and Technology Projects in Guangzhou 2024B03J0904
6 · The paper itself

Abstract

Triggering receptor expressed on myeloid cells 2 (TREM2) located on microglial membranes and its downstream PI3K/PKB signaling pathway are involved in epilepsy. We have synthesized a novel carbazole-based H

Indexed as

AnticonvulsantsHydrogen SulfideMembrane GlycoproteinsPilocarpineReceptors, ImmunologicSeizuresSignal TransductionAnimalsCarbazolesHippocampusMaleMiceMice, Inbred C57BLMice, KnockoutAnticonvulsantsCarbazolesHydrogen SulfideMembrane GlycoproteinsPilocarpineReceptors, ImmunologicTrem2 protein, mouseEpilepsyHydrogen sulfide (H2S)Microglial polarizationNeuroinflammationTriggering receptor expressed on myeloid cells 2 (TREM2)

Identifiers

PMID41212272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.