Evidence map›Paper›PMID 41212179›Full record

ArticleSchizophrenia bulletin2026

Neighborhood Characteristics and Social Functioning: Exploring Shared and Distinct Psychosocial Pathways Among Individuals at Clinical High-Risk for Psychosis.

Qingyue E Yuan, Cope Feurer, Qing D Zhou, Ricardo Carrion, Jean Addington, Carrie E Bearden, Kristin S Cadenhead, Tyrone D Cannon, Barbara A Cornblatt, Matcheri Keshavan and 6 more

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qingyue E YuanDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, United States.ORCID 0009-0002-6775-5080
Cope FeurerDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC 27514, United States.
Qing D ZhouDepartment of Psychology, Emory University, Atlanta, GA 30322, United States.
Ricardo CarrionDivision of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY 11004, United States.
Jean AddingtonDepartment of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N4N1, Canada.
Carrie E BeardenDepartments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90024, United States.ORCID 0000-0002-8516-923X
Kristin S CadenheadDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.ORCID 0000-0002-5952-4605
Tyrone D CannonDepartment of Psychiatry, Yale University, New Haven, CT 06511, United States.
Barbara A CornblattDivision of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY 11004, United States.
Matcheri KeshavanDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston, MA 02215, United States.
Daniel H MathalonDepartment of Psychiatry, University of California, San Francisco, CA 94143, United States.
Diana O PerkinsDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC 27514, United States.
William S StoneDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center, Boston, MA 02215, United States.ORCID 0000-0003-2932-7288
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT 06511, United States.
Elaine F WalkerDepartment of Psychology, Emory University, Atlanta, GA 30322, United States.ORCID 0000-0002-9798-8101
Benson S KuDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, United States.

Funding

1/9 Predictors and Mechanisms of Conversion to PsychosisU01MH081902 · NIMH · YALE UNIVERSITY · PI CANNON, TYRONE D · 2008 to 2018
$12.4M
5/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082004 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERKINS, DIANA O. · 2008 to 2018
$7.5M
Administrative Supplement Harmonization of At Risk Multisite Observational Networks for Youth(HARMONY)U01MH081928 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STONE, WILLIAM SETH · 2008 to 2018
$7.1M
4/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081857 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORNBLATT, BARBARA A. · 2008 to 2018
$6.2M
8/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082022 · NIMH · YALE UNIVERSITY · PI WOODS, SCOTT W · 2008 to 2018
$6.0M
2/9 - Predictors and Mechanisms of Conversion to PsychosisU01MH081988 · NIMH · EMORY UNIVERSITY · PI WALKER, ELAINE FRAN · 2008 to 2018
$5.4M
6/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081944 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CADENHEAD, KRISTIN S. · 2008 to 2018
$4.9M
"7/9" Predictors and Mechanisms of Conversion to PsychosisU01MH081984 · NIMH · UNIVERSITY OF CALGARY · PI ADDINGTON, JEAN M · 2008 to 2018
$4.2M
9/9-Predictors and Mechanisms of Conversion to PsychosisU01MH076989 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MATHALON, DANIEL H · 2014 to 2018
$3.9M
Brain-Behavioral Predictors of Interpersonal Stress Generation and Depression Risk in Adolescent GirlsK23MH129564 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Cope Feurer · 2022 to 2026
$1.0M
Impact of Neighborhood Characteristics on Conversion to Psychosis among Youth at Clinical High Risk for PsychosisK23MH129684 · NIMH · EMORY UNIVERSITY · PI Benson Ku · 2022 to 2026
$970k
NIMH NIH HHS K23 MH129564NIMH NIH HHS K23 MH129684NIMH NIH HHS U01 MH076989NIMH NIH HHS U01MH076989NIMH NIH HHS U01 MH081857NIMH NIH HHS U01 MH081902NIMH NIH HHS U01MH081902NIMH NIH HHS U01 MH081928NIMH NIH HHS U01MH081928NIMH NIH HHS U01 MH081944NIMH NIH HHS U01MH081944NIMH NIH HHS U01 MH081984NIMH NIH HHS U01MH081984NIMH NIH HHS U01 MH081988NIMH NIH HHS U01MH081988NIMH NIH HHS U01 MH082004NIMH NIH HHS U01MH082004NIMH NIH HHS U01 MH082022NIMH NIH HHS U01MH082022NIMH NIH HHS UO1MH081857
6 · The paper itself

Abstract

background and hypothesisRecent research suggests that environmental factors may contribute to psychosis through at least partially distinct pathways. This study examined how neighborhood socioeconomic deprivation and social fragmentation relate to impaired social functioning in individuals at clinical high risk for psychosis (CHR-P) via social and contextual risk factors. STUDY

designData were collected from the North American Prodrome Longitudinal Study Phase 3. Neighborhood characteristics were geocoded using participant addresses at baseline. Social and contextual risk factors were derived from the Structural Assessment of Violence Risk in Youth. Social functioning was measured using the Global Assessment of Functioning: Social Scale. STUDY

resultsNeighborhood social fragmentation was associated with greater peer rejection (β = 0.11; 95% CI, 0.01-0.22, P = .034), which, in turn, was negatively associated with social functioning (β = -0.18; 95% CI, -0.23 to -0.12, P < .001). Both neighborhood social fragmentation (β = 0.18; 95% CI, 0.03-0.33, P = .022) and neighborhood socioeconomic deprivation (β = 0.34; 95% CI, 0.21-0.48, P < .001) were associated with greater community disorganization, which was negatively associated with social functioning (β = -0.08; 95% CI, -0.17 to -0.01, P = .046). Neighborhood socioeconomic deprivation had a direct negative association with social functioning (β = -0.15; 95% CI, -0.29 to -0.02, P = .03).

conclusionsThis study identified shared and distinct pathways relating neighborhood characteristics to impaired social functioning among CHR-P individuals. Understanding how environmental factors impact social functioning may help develop effective interventions for youth at high risk.

Indexed as

Neighborhood CharacteristicsPsychological DistancePsychosocial FunctioningPsychotic DisordersSocial DeprivationAdolescentFemaleHumansLongitudinal StudiesMaleProdromal SymptomsRiskRisk FactorsSocioeconomic Disparities in HealthYoung Adultclinical high riskneighborhood disadvantagepsychosispsychosocial factorssocial fragmentationsocioeconomic deprivation

Identifiers

PMID41212179
PMCPMC13050290

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