Evidence map›Paper›PMID 41211974›Full record

ArticleJournal of virology2025

A SUMO interacting motif in the replication initiator protein of tomato yellow leaf curl virus is required for viral replication.

Nicolas Frédéric Gaertner, Francesca Maio, Manuel Arroyo-Mateos, Ana P Luna, Blanca Sabarit, Mark Kwaaitaal, Sandra Eltschkner, Marcel Prins, Eduardo R Bejarano, Harrold A van den Burg

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicolas Frédéric Gaertner *Molecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0009-0008-8119-9432
Francesca Maio *Molecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.
Manuel Arroyo-MateosMolecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-6936-2198
Ana P LunaDept. Biología Celular, Genética y Fisiología, Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora", Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, Spain.ORCID 0000-0002-8230-3229
Blanca SabaritDept. Biología Celular, Genética y Fisiología, Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora", Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, Spain.ORCID 0000-0003-0614-3347
Mark KwaaitaalMolecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.
Sandra EltschknerMolecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-9854-0800
Marcel PrinsMolecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-0318-731X
Eduardo R BejaranoDept. Biología Celular, Genética y Fisiología, Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora", Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, Spain.ORCID 0000-0002-4806-253X
Harrold A van den BurgMolecular Plant Pathology, Swammerdam Institute for Life Sciences, research theme Green Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-4142-374X

Funding

Ministerio de Cienca y Tecnologia PID2022-1393760B31Top Sector Agri and Food 1409-036Top Sector Agri and Food 19157
6 · The paper itself

Abstract

Circular Rep-encoding single-stranded (CRESS)-DNA viruses comprise a diverse group of viruses that use rolling-circle replication to copy their genomes. They infect organisms in almost all branches of the eukaryotic tree of life. A hallmark of all CRESS-DNA viruses is the presence of a single conserved protein, the replication initiator protein (Rep), that orchestrates viral replication by exploiting the host DNA replication machinery. In the case of the plant-infecting

Indexed as

BegomovirusDNA HelicasesSUMO-1 ProteinTrans-ActivatorsViral ProteinsVirus ReplicationAmino Acid MotifsArabidopsisArabidopsis ProteinsDNA ReplicationNicotianaPlant DiseasesProtein BindingSolanum lycopersicumArabidopsis ProteinsDNA Helicasesreplication initiator proteinSUMO-1 ProteinTrans-ActivatorsViral ProteinsATPase activitybegomovirusC1CRESS-DNA virusDNA replicationgeminivirusRepSCE1SUMOsystemic movementTGMVTYLCVvirus replication

Identifiers

PMID41211974
PMCPMC12724345

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.