Evidence map›Paper›PMID 41211856›Full record

ArticlePlant biotechnology journal2026

Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1.

Amélie A Kelly, Martin Fulda, Merle Aden, Ilka N Abreu, Kirstin Feussner, Ivo Feussner

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adaptive cold-environmental strategies ofHorticulture research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amélie A KellyDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.ORCID https://orcid.org/0000-0003-2142-9327
Martin FuldaDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.ORCID https://orcid.org/0000-0001-5734-067X
Merle AdenDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.
Ilka N AbreuDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.ORCID https://orcid.org/0000-0003-4728-0161
Kirstin FeussnerDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.ORCID https://orcid.org/0000-0003-1634-8258
Ivo FeussnerDepartment for Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, Germany.ORCID https://orcid.org/0000-0002-9888-7003

Funding

Bundesministerium für Bildung und Forschung 031B0343ADeutsche Forschungsgemeinschaft INST 186/1434-1Deutsche Forschungsgemeinschaft ZUK 45/2010
6 · The paper itself

Abstract

Sinapine (O-sinapoyl choline) is the major phenolic metabolite typically found in the oil-rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock. To improve Camelina flour for human consumption or as animal feed, we reduced sinapine content through CRISPR/Cas9-based genome editing of REF1 (REDUCED EPIDERMAL FLUORESCENCE1), which encodes the NADP

Indexed as

BrassicaceaeCholineGene EditingPlant ProteinsSeedsCRISPR-Cas SystemsPlants, Genetically ModifiedCholinePlant ProteinssinapineCamelinachlorogenic acidgenome editingleavesmetabolite profilingseedssinapine

Identifiers

PMID41211856
PMCPMC12946524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.