Trial reportOrthodontics & craniofacial research2026
Mandibular Advancement in Dentofacial Orthopaedics: Effects on Pharyngeal Airway, Dentoskeletal Characteristics and Quality of Life: A Randomised Controlled Trial.
Trial report in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03455634 (Treatment of Malocclusion Class II/1 - Predictors for Seeking, Compliance and Outcome), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Malocclusion Class II/1 - Predictors for Seeking, Compliance and Outcome
Who cites it
2 citing papers in PubMed.
- Development and Validation of a Patient-Reported Outcome Questionnaire for Children Undergoing Removable Orthodontic Treatment.Dentistry journal · 2026Article
- Scientific overview of mandibular advancement devices: a bibliometric and altmetric analysis.Dental press journal of orthodontics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveTo explore which effects of jaw orthopaedics in class II during puberty are related to daily functioning and family impacts. MATERIALS AND
methodsSeventy-one subjects in their pre-pubertal and peri-pubertal stages with skeletal class II and procumbent incisors (median age 12 years; 56% females) were treated with the Sander bite jumping appliance (BJA; N = 37) and Twin block (TB; N = 35). They were matched by the same number of untreated class II subjects. Lateral cephalograms before and after treatment (one-year distance) were analysed. Children's and parental perspectives of oral health-related quality of life (OHRQoL) were assessed by the Child Perceptions Questionnaire, Parental-Caregiver Perceptions Questionnaire and Family Impact Scale
resultsThe change in pharyngeal airway width in treated groups was not significantly greater than in the group without orthodontic treatment. Treated groups, compared to the untreated group, demonstrated an increase in mandibular length and a reduction in sagittal skeletal intermaxillary discrepancy (p ≤ 0.002). Retroclination of the maxillary incisors, accompanied by a reduction in overjet, overbite and upper lip prominence, was observed in both treated groups compared to the untreated (p ≤ 0.001). Parents of children in the TB group reported a reduction in impairment of OHRQoL when compared to BJA (p = 0.003). There were no correlations between the change in the airway width, dentofacial characteristics and OHRQoL.
conclusionTreatment with both appliances stimulated mandibular growth, retroclined maxillary incisors and improved facial profile and OHRQoL. However, the changes in the airway were not greater than normal growth and were not related to alterations in other dentofacial characteristics or OHRQoL.
trial registrationClinicalTrials.gov identifier: NCT03455634.
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