Evidence map›Paper›PMID 41211688›Full record

ArticleThe International journal of eating disorders2026

Predictors of Treatment Outcome in an Early Intervention Eating Disorder Sample.

Karina L Allen, Amelia Austin, Michaela Flynn, Danielle Glennon, Victoria A Mountford, Amy Brown, Mary Franklin-Smith, William Rhys Jones, Gabrielle Brady, Nicole Nunes and 4 more

Abstract readClinical Study
In one paragraph

Article in The International journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Karina L AllenSouth London and Maudsley NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-2896-6459
Amelia AustinCentre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0002-4979-4847
Michaela FlynnCentre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-0208-1492
Danielle GlennonSouth London and Maudsley NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-0704-8619
Victoria A MountfordSage Clinics, Dubai, UAE.ORCID https://orcid.org/0000-0002-1932-1723
Amy BrownSussex Partnership NHS Foundation Trust, UK.ORCID https://orcid.org/0000-0001-6994-1472
Mary Franklin-SmithLeeds and York Partnership NHS Foundation Trust, Leeds, UK.
William Rhys JonesCentral and North West London NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0001-9516-5534
Gabrielle BradyNorth East London NHS Foundation Trust, London, UK.
Nicole NunesNorth East London NHS Foundation Trust, London, UK.
Frances ConnanNorth East London NHS Foundation Trust, London, UK.
Kate MahonyUniversity College London, Division of Psychology and Language Sciences, London, UK.
Lucy SerpellUniversity College London, Division of Psychology and Language Sciences, London, UK.ORCID https://orcid.org/0000-0001-8543-8383
Ulrike SchmidtSouth London and Maudsley NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-1335-1937

Funding

Academic Health Science NetworkHealth FoundationKCL International Postgraduate Research ScholarshipsMedical Research Council MR/X030539/1NHS EnglandNIHR Maudsley Biomedical Research CentreO'Brien Institute for Public Health Postdoctoral Scholar AwardThe Cumming School of Medicine Postdoctoral Fellow AwardUK Research and Innovation MR/W002418/1
6 · The paper itself

Abstract

objectiveTo examine baseline predictors of treatment completion and clinical outcomes in 16 to 25-year-olds referred for early intervention for a recent-onset eating disorder (ED).

methodParticipants (n = 228; 93% female, 63% White British) were drawn from the FREED-Up study, which evaluated First episode Rapid Early intervention for EDs (FREED) in England across 2017-2018. Measures were completed at baseline and 3-, 6- and 12-months. Generalized estimating equations were used to identify baseline predictors of treatment completion and symptom remission by 12-months. Linear mixed models were used to identify baseline predictors of change in global eating disorder examination-questionnaire (EDE-Q) scores, binge eating, purging and BMI (anorexia nervosa [AN] only) over 12-months. Possible predictors included baseline ED symptoms, depression, anxiety, stress, psychosocial impairment, expressed emotion from close others, functioning against personalized goals, age, ethnicity, duration of illness, waiting times and BMI.

resultsThere were no significant predictors of treatment completion. Lower stress at baseline predicted increased likelihood of symptom remission by 12 months. Lower purging and psychosocial impairment at baseline predicted lower Global EDE-Q scores over the following 12 months; lower purging predicted lower rates of binge eating; and lower Global EDE-Q scores, binge eating and assessment waiting times predicted lower rates of purging. Higher purging at baseline was associated with higher BMI in AN. DISCUSSION: This study provides new data on predictors of treatment outcomes in an early intervention ED sample. In addition to ED symptoms and waiting times, psychosocial impairment and stress warrant consideration as factors that may influence treatment outcomes.

Indexed as

Early Medical InterventionFeeding and Eating DisordersFeeding BehaviorSocial BehaviorAdolescentAdultBody Mass IndexFemaleHumansLinear ModelsMaleRisk FactorsSocial Behavior DisordersStress, PsychologicalSurveys and QuestionnairesTime Factorsanorexia nervosabulimia nervosaearly interventioneating disordersemerging adulthoodother specified feeding or eating disorderpsychological therapytreatment outcomes

Identifiers

PMID41211688
PMCPMC12979957

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.