Evidence map›Paper›PMID 41211620›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Overcoming Hydrophobicity with Water Enables Ultrafast Hydrolysis of Waste Polyethylene Terephthalate at Very Mild Conditions.

Francesco Millucci, Raimondo Germani, Leonardo Colelli, Serena Gabrielli, Paola Sassi, Anna Donnadio, Martina Conti, Silvia Corezzi

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco MillucciDipartimento di Fisica e Geologia, Università di Perugia, Perugia, I-06123, Italy.ORCID https://orcid.org/0009-0004-5565-3735
Raimondo GermaniDipartimento di Chimica, Biologia e Biotecnologie, Università di Perugia, Perugia, I-06123, Italy.ORCID https://orcid.org/0000-0001-7076-7475
Leonardo ColelliDepartment of Chemical Engineering Materials Environment, "Sapienza" University of Rome, Rome, I-00184, Italy.ORCID https://orcid.org/0009-0009-6293-171X
Serena GabrielliChemistry Interdisciplinary Project (ChIP), Scuola di Scienze e Tecnologie, Università di Camerino, Camerino, I-62032, Italy.ORCID https://orcid.org/0000-0002-2048-5813
Paola SassiDipartimento di Chimica, Biologia e Biotecnologie, Università di Perugia, Perugia, I-06123, Italy.ORCID https://orcid.org/0000-0002-4920-2784
Anna DonnadioDipartimento di Scienze Farmaceutiche, Università di Perugia, Perugia, I-06123, Italy.ORCID https://orcid.org/0000-0003-2903-4135
Martina ContiCNR - Istituto Officina dei Materiali (IOM), Area Science Park Basovizza, Trieste, I-34149, Italy.ORCID https://orcid.org/0000-0002-7968-1560
Silvia CorezziDipartimento di Fisica e Geologia, Università di Perugia, Perugia, I-06123, Italy.ORCID https://orcid.org/0000-0002-3437-5949

Funding

European Union ECS00000041 - VITALITY - CUP J97G22000170005Italian Ministry of University and Research (MUR) REACT-EU - PON R&I 2014-2020
6 · The paper itself

Abstract

Chemical recycling of plastics holds great promise but remains constrained by sustainability issues, with polyethylene terephthalate (PET) epitomizing this challenge. Herein, we introduce a conceptually novel strategy that overcomes PET's intrinsic hydrophobicity by physically re-engineering the polymer's microstructure to enable ultrafast alkaline hydrolysis under exceptionally mild conditions. We leverage the ability of propylene carbonate (PC)-an inexpensive, commercial, green solvent-to selectively dissolve PET, to thermally induce phase separation, and subsequently act as a carrier for water insertion between polymer chains. Upon complete PC replacement, the water uptake exceeds twice the polymer mass, preventing chain re-compaction and establishing an interfacial environment that facilitates hydroxyl ion diffusion to ester bonds and depolymerization with minimal alkali consumption. As a result, water-swollen PET fully depolymerizes (96% TPA yield) at atmospheric pressure within 5 min at 90

Indexed as

Alkaline hydrolysisChemical recyclingHydrophobicityMild conditionsWater‐swollen PET

Identifiers

PMID41211620
PMCPMC12759205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.