Evidence map›Paper›PMID 41211613›Full record

Trial reportInfluenza and other respiratory viruses2025

Obesity in Recovery From Influenza-Like Illness and Effectiveness of Oseltamivir.

Oanh Ngoc Nguyen, Nathaly Garzón-Orjuela, Alike W van der Velden, Christopher C Butler, Akke Vellinga

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oanh Ngoc NguyenCARA Network, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0009-0001-9434-292X
Nathaly Garzón-OrjuelaCARA Network, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0001-6181-8154
Alike W van der VeldenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0002-9443-2837
Christopher C ButlerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0102-3453
Akke VellingaCARA Network, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0002-6583-4300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResults from observational studies have shown that obesity has a mild to moderate association with influenza-like illness (ILI) severity and hospitalization risk. Using data from the ALIC

methodsA total of 2622 adults (≥ 18 years old) from the ALIC

resultsAt presentation, ILI symptom severity was not different between weight groups. However, time to recovery was longer for obese patients compared to under/normal weight patients, with adjusted HR 0.88 (95% CI 0.79-0.99). The mean time to recovery was 6.6 days (95% CI 6.0-7.1) for obese patients, 6.2 days (95% CI 5.8-6.6) for overweight, and 5.7 days (95% CI 5.4-6.1) for under/normal weight patients. Obese patients had similar benefits from oseltamivir treatment compared to under/normal weight patients, with an average of 0.8 days gained from oseltamivir (95% CI 0.7-1) and 0.5 days (95% CI 0.4-0.7), respectively.

conclusionsILI symptom severity at presentation was equally distributed between the three weight groups. However, their time to recovery was approximately 1 day longer compared to under/normal weight patients. The effectiveness of oseltamivir appears to be similar between the two groups.

Indexed as

Antiviral AgentsInfluenza, HumanObesityOseltamivirAdultAgedBody Mass IndexFemaleHumansMaleMiddle AgedSeverity of Illness IndexTreatment OutcomeYoung AdultAntiviral AgentsOseltamivirinfluenza‐like illnessobesityoseltamivirrecovery adultsseverity

Identifiers

PMID41211613
PMCPMC12598495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.