Evidence map›Paper›PMID 41211563›Full record

ReviewFood science and biotechnology2025

Selected medium-chain dicarboxylic acids: alternative preservatives in improving shelf-life and quality of meat products.

Zhengrui Liao, Yu-Kee Yeoh, Zhizhong Xiao, Xiaotong Zhu, Thaigarajan Parumasivam, Thuan-Chew Tan, Vigneswary Gunasangar

Abstract readReview
In one paragraph

Review in Food science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengrui LiaoFood Technology Division, School of Industrial Technology, Universiti Sains Malaysia, George Town, Malaysia.ORCID 0000-0001-7942-7354
Yu-Kee YeohInstitute of Professional Development, Open University Malaysia, Petaling Jaya, Malaysia.
Zhizhong XiaoSchool of Pharmacy, China Pharmaceutical University, Nanjing, China.
Xiaotong ZhuCollege of Animal Sciences, South China Agricultural University, Guangzhou, China.
Thaigarajan ParumasivamSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Malaysia.
Thuan-Chew TanFood Technology Division, School of Industrial Technology, Universiti Sains Malaysia, George Town, Malaysia.
Vigneswary GunasangarFood Technology Division, School of Industrial Technology, Universiti Sains Malaysia, George Town, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmaceutical industry finds succinic acid (SUA), glutaric acid (GLA), and azelaic acid (AZA) to be highly attractive and practicable due to their outstanding biological qualities, which include glucose control, antioxidant, anti-inflammatory, and antibacterial properties. Moreover, the routine use of organic acids in meat processing offers a practical, cost-effective, and safe method for extending the shelf life and ensuring the safety of meat products. The FDA generally deems them safe, and there are no daily intake limits, supporting their widespread use. Many dicarboxylic acids and their salts have been reported to be employed as food additives, either purposefully or inadvertently, due to their safety and other properties. Nowadays, the "medicine and food homology" area is one of the innovations that enables them to enter the food industry. However, food and pharmaceuticals underestimate the scope of their bacteriostatic and antioxidant applications. This review highlights the multifaceted benefits and applications of SUA, GLA, and AZA, especially in meat preservation. Their physicochemical properties, antimicrobial and antioxidant capabilities, and metabolism in the human body present them as viable alternatives to conventional meat preservatives. Further research into their synergistic effects, optimal concentrations, and regulatory compliance will be crucial for their successful implementation in the meat industry.

Indexed as

AntimicrobialAzelaic acidGlutaric acidMeatPreservationSuccinic acid

Identifiers

PMID41211563
PMCPMC12589724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.