ArticleFood science and biotechnology2025
Whey-enhanced serum-free medium for bovine myoblast expansion.
Article in Food science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Food-grade utilization of bovine slaughterhouse by-products for developing cost-effective media supplements in cultivated meat applications.Food science of animal resources · 2026Review
- Exploring ethical, sustainable and effective foetal bovine serum alternatives forFrontiers in toxicology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-based foods are anticipated to be a sustainable alternative to animal protein sources. The primary challenge is developing a food-grade serum-free medium (SFM) that is affordable, safe, acceptable to consumers, and available in large quantities. This study was conducted to develop such a medium using food ingredients dissolved in water that support the expansion of bovine myoblasts and maintain their differentiation capability. Through screening of various food ingredients, whey was identified as the most effective component. Whey improved myoblast proliferation in SFM to levels than those in a serum-containing medium. The differentiation capability of myoblasts cultured in whey-containing SFM was similar to that in serum-containing medium. Remarkably, whey could support myoblast proliferation even after heat treatment, allowing for the sterilization of whey-containing media by heat treatment, a common process in food processing. Hence, whey could be an ideal ingredient for affordable food-grade serum replacement in cell-based food production.
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Registered trials
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