Evidence map›Paper›PMID 41211519›Full record

ArticleHealth science reports2025

Differential Expression of Galectin-3, Caspase-1, and Phosphorylated P53: Diagnostic Biomarkers for Basal Cell Carcinoma: A Case-Control Study.

Mahsa Niamoradi, Fatemeh Babajani, Seyed Askar Roghani, Mohammad Taghi Goodarzi, Soheila Asadi

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Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahsa NiamoradiDepartment of Biochemistry, Sha.C. Islamic Azad University Shahrood Iran.
Fatemeh BabajaniDepartment of Clinical Biochemistry Kermanshah University of Medical Sciences Kermanshah Iran.ORCID https://orcid.org/0000-0001-6714-5309
Seyed Askar RoghaniClinical Research Development Center, Imam Reza Hospital Kermanshah University of Medical Science Kermanshah Iran.
Mohammad Taghi GoodarziDepartment of Biochemistry, Sha.C. Islamic Azad University Shahrood Iran.ORCID https://orcid.org/0000-0002-5546-5812
Soheila AsadiDepartment of Clinical Biochemistry Kermanshah University of Medical Sciences Kermanshah Iran.ORCID https://orcid.org/0000-0002-1974-6860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Basal cell carcinoma (BCC) is a common form of skin cancer. By considering the role of Galectin-3 (Gal-3), Caspase-1, and Phosphorylated p53 (pP53), they might have an essential role in BCC development. This study aimed to examine the genes and their corresponding proteins in the tumor tissue of patients with BCC and compare them to those in the tumor margins. Furthermore, their potential roles as biomarkers were evaluated. Materials and Methods: The gene expression of Results: Our findings indicated the increased Conclusion: The upregulation of

Indexed as

IL‐1βNF‐κBoxidative stressreactive oxygen speciesskin malignanciestumor microenvironmentultraviolet radiation

Identifiers

PMID41211519
PMCPMC12592677

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.