Evidence map›Paper›PMID 41211514›Full record

ArticleHealth science reports2025

Innovative Applications of Marine Macroalgae Polysaccharides in Tissue Engineering and Drug Delivery: A Review Study.

Foroozan Jalalibidgoli, Pardis Irankhahi, Helia Hajihassani, Ali Akbar Ghotbi-Ravandi

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Foroozan JalalibidgoliDepartment of Cell & Molecular Biology, Faculty of Life Sciences and Biotechnology Shahid Beheshti University Tehran Iran.ORCID https://orcid.org/0009-0005-9812-569X
Pardis IrankhahiDepartment of Plant Sciences and Biotechnology, Faculty of Life Sciences and Biotechnology Shahid Beheshti University Tehran Iran.ORCID https://orcid.org/0000-0001-8130-891X
Helia HajihassaniDepartment of Cell & Molecular Biology, Faculty of Life Sciences and Biotechnology Shahid Beheshti University Tehran Iran.ORCID https://orcid.org/0000-0002-7091-1091
Ali Akbar Ghotbi-RavandiDepartment of Plant Sciences and Biotechnology, Faculty of Life Sciences and Biotechnology Shahid Beheshti University Tehran Iran.ORCID https://orcid.org/0000-0002-9937-7232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Marine macroalgae are abundant sources of bioactive polysaccharides-including alginate, fucoidan, ulvan, carrageenan, and agarose-widely recognized for extensive biomedical applications. These polysaccharides exhibit remarkable biological properties, such as immunostimulatory, anticancer, antioxidant, antimicrobial, and anti-inflammatory effects, while maintaining low toxicity. Methods: A systematic literature review identified 281 studies examining sulfated polysaccharides derived from marine algae and their implementation in bioengineering fields, including tissue engineering and drug delivery applications. Results: Marine-derived polysaccharides exhibit biocompatibility, biodegradability, and multifunctionality, making them highly suitable for developing hydrogels, nanoparticles, microspheres, and other biomaterial platforms. Their inherent structural diversity supports targeted modification for enhanced mechanical stability, drug release kinetics, and cellular interactions. Conclusion: Polysaccharides extracted from marine macroalgae represent a versatile resource for developing biomaterials in tissue engineering and drug delivery. Their multifunctional properties and adaptability position them as key materials in advancing biomedical research and addressing complex healthcare needs.

Indexed as

bioengineeringdrug deliverymarine algaesulfated polysaccharidestissue designwound dressing

Identifiers

PMID41211514
PMCPMC12592692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.