Evidence map›Paper›PMID 41211478›Full record

ArticleFrontiers in rehabilitation sciences2025

Does body weight support improve neural and biomechanical measures during treadmill gait in children with unilateral cerebral palsy?

Rajit Banerjee, Yushin Kim, Thomas C Bulea, Diane L Damiano

Abstract read
In one paragraph

Article in Frontiers in rehabilitation sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajit BanerjeeRehabilitation Medicine Department, Neurorehabilitation and Biomechanics Research Section, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Yushin KimRehabilitation Medicine Department, Neurorehabilitation and Biomechanics Research Section, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Thomas C BuleaRehabilitation Medicine Department, Neurorehabilitation and Biomechanics Research Section, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Diane L DamianoRehabilitation Medicine Department, Neurorehabilitation and Biomechanics Research Section, National Institutes of Health Clinical Center, Bethesda, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Body weight support (BWS) treadmill training, commonly utilized to improve gait, has inconsistent evidence of effectiveness across disorders. Methods: We aimed to comprehensively evaluate its scientific rationale by comparing immediate effects of two weight support levels (20%, 40%) to unsupported (0%) treadmill walking on neural and biomechanical measures in children with unilateral cerebral palsy (CP) and typical development (TD). We hypothesized BWS would demonstrate positive effects only in CP. Participants included 10 with TD and 8 with CP (mean age = 14.6 and 15.4 years, respectively). Results: Minimal or no group differences or BWS effects were found for synergy number, structure or Walk-DMC, whereas the Gait Deviation Index (GDI) showed a significant interaction with 20% BWS where the dominant side in CP improved with 20% BWS while both sides in TD worsened. Beta band EEG activation from 0% to 20% BWS showed a significant triple interaction increasing in the non-dominant and decreasing in the dominant hemisphere in TD, while increasing in both in CP. A worsening trend was seen with 40% BWS in all measures except z scores. Conclusion: BWS has beneficial effects on kinematics in CP supporting the basic premise for use in neurorehabilitation at the body structure level.

Indexed as

electroencephalographykinematicsmuscle synergiesnon-negative matrix factorizationtemporal-spatialunloading

Identifiers

PMID41211478
PMCPMC12588987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.