Evidence map›Paper›PMID 41211471›Full record

ArticlePulmonary circulation2025

Incremental Burden of Pulmonary Hypertension Among Patients With Interstitial Lung Disease in the Real-World Setting.

Charles D Burger, Jasmanda Wu, Gerald O'Brien, Natalya Makulova, Trevor Ward, Meghana G Shamsunder, Bonny Shah, Zeenat Safdar

Abstract read
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charles D BurgerMayo Clinic Jacksonville Florida USA.
Jasmanda WuInsmed Incorporated Bridgewater New Jersey USA.
Gerald O'BrienInsmed Incorporated Bridgewater New Jersey USA.
Natalya MakulovaInsmed Incorporated Bridgewater New Jersey USA.
Trevor WardPanalgo Boston Massachusetts USA.
Meghana G ShamsunderPanalgo Boston Massachusetts USA.
Bonny ShahInsmed Incorporated Bridgewater New Jersey USA.
Zeenat SafdarHouston Methodist Lung Center Houston Texas USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a common complication in interstitial lung disease (ILD), but the additional burden it imposes on patients and healthcare systems is not well characterized. This retrospective analysis of claims data from the US Merative MarketScan database assessed hospitalization rates and costs over 2 years in patients with connective tissue disease-related ILD (CTD-ILD) and non-CTD-ILD with or without PH (between January 2017 and December 2019). Index was the date of first ILD claim; baseline was the 12-month preindex period. In total, 16,129 patients with non-CTD-ILD (1502 [9%] with PH) and 4545 patients with CTD-ILD (663 [15%] with PH) were identified. A higher proportion of patients with non-CTD-ILD with PH, compared with patients without PH, had all-cause and heart failure (HF)-related hospitalizations during baseline (all-cause, 37.0% vs. 22.3%; HF-related, 14.2% vs. 3.1%), 0-12 months (62.4% vs. 43.0%; 29.0% vs. 7.0%), and 13-24 months (44.7% vs. 18.3%; 21.5% vs. 3.2%) follow-up (

Indexed as

connective tissue diseasehealthcare resource utilizationhospitalizationinterstitial lung diseasepulmonary hypertension

Identifiers

PMID41211471
PMCPMC12590488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.