ArticleInternational journal of clinical pediatric dentistry2025
Comparative Evaluation of Remineralization Efficacy of a Novel Proanthocyanidin Biovarnish with Fluoride Varnish on Primary Teeth: An
Article in International journal of clinical pediatric dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Biomimetic Strategies for Subsurface Enamel Remineralization: Depth-Dependent Effects of Biomimetic Agents Compared with Fluoride.Biomimetics (Basel, Switzerland) · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims and background: Early dental caries are caused by subsurface demineralization of enamel and manifests 0.0015 as noncavitated, white lesions. Remineralization is a process that replaces lost mineral ions in demineralized enamel. Saliva naturally aids in remineralization. However, this process is slow and can be hampered under cariogenic conditions. Fluoride has been a significant caries-preventive agent, promoting remineralization, and preventing demineralization. However, interest in non-fluoridated treatments has increased due to concerns about dental fluorosis. Proanthocyanidins (PACs), which are extracted from grape seeds, have remineralization potential owing to their capacity to chelate calcium and phosphate ions. Materials and methods: This study examined the remineralization effectiveness of a fluoride varnish and a PAC biovarnish on artificially induced dental caries Results: One-way ANOVA (analysis of variance) revealed significant differences ( Conclusion: The novel PAC biovarnish demonstrated superior remineralization efficacy compared with fluoride varnish, suggesting it as a promising alternative for fluoridated caries prevention treatments. Clinical significance: The study demonstrates that PAC biovarnish is a highly effective alternative to fluoride varnish for enamel remineralization, potentially reducing the risk of dental fluorosis. This offers a promising nonfluoridated option for caries prevention and management. How to cite this article: Baskar R, Srinivasan D, Eagappan AR S,
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