Evidence map›Paper›PMID 41211312›Full record

ArticlePeerJ2025

The role of pre-pregnancy overweight in gestational diabetes, hypertension, and macrosomia: a retrospective study.

Sisi Zhu, LiFeng Chen, LiJuan Shen, Xiangxiang Fu

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Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sisi ZhuYuyao Maternity and Child Health Care Hospital (Yuyao Second People's Hospital), Ningbo, China.
LiFeng ChenYuyao Maternity and Child Health Care Hospital (Yuyao Second People's Hospital), Ningbo, China.
LiJuan ShenYuyao Maternity and Child Health Care Hospital (Yuyao Second People's Hospital), Ningbo, China.
Xiangxiang FuYuyao Maternity and Child Health Care Hospital (Yuyao Second People's Hospital), Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Adverse pregnancy outcomes, including gestational diabetes mellitus (GDM), gestational hypertension (GHp), macrosomia, preterm birth, and low birth weight, pose significant risks to maternal and neonatal health. Pre-pregnancy overweight is a modifiable risk factor for these outcomes. However, comprehensive analyses of multiple adverse outcomes and their dose-response relationships with pre-pregnancy body mass index (BMI) remain limited. Methods: This retrospective cohort study included 748 women with singleton pregnancies who delivered at Yuyao Maternal and Child Health Hospital from January 1, 2022, to December 31, 2022. Participants were categorized into normal-weight and overweight groups based on pre-pregnancy BMI. Logistic regression models were used to evaluate associations between overweight and adverse pregnancy outcomes, adjusting for confounding variables. Restricted cubic spline (RCS) regression was employed to investigate dose-response relationships between BMI and pregnancy outcomes. Results: Pre-pregnancy overweight was significantly associated with higher risks of GDM (adjusted OR = 3.122, 95% CI [1.754-5.557], Conclusion: Pre-pregnancy overweight is a significant modifiable risk factor for adverse maternal and neonatal outcomes, particularly GDM, GHp, and macrosomia. These findings underscore the importance of integrating BMI monitoring and personalized weight management strategies into pre-pregnancy care programs to mitigate risks and improve maternal and neonatal health outcomes.

Indexed as

Diabetes, GestationalFetal MacrosomiaHypertension, Pregnancy-InducedOverweightAdultBody Mass IndexFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsAdverse pregnancy outcomesGestational diabetes mellitusGestational hypertensionMacrosomiaPre-pregnancy overweight

Identifiers

PMID41211312
PMCPMC12591048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.