ArticleFrontiers in neurology2025
The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with neuromyelitis optica spectrum disorders and multiple sclerosis.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association of Glycemic Status with Disability, Relapse Activity, Inflammatory Markers, and Metabolic Profile in Patients with Multiple Sclerosis.Journal of clinical medicine · 2026Article
- Changes in Blood Cells and Complements During Relapse Prevention Therapies for Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder.International journal of molecular sciences · 2026Article
- Predictors for the severity of acute aquaporin-4 immunoglobulin G-seropositive neuromyelitis optica spectrum disorders: a prospective cohort study.Frontiers in immunology · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to investigate the differences in neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) between patients with neuromyelitis optica spectrum disorders (NMOSDs) and multiple sclerosis (MS), as well as their potential associations with disease onset and progression. Methods: Clinical, laboratory, and imaging data of NMOSD and MS patients admitted to Peking University Third Hospital were retrospectively analyzed. Blood test results within 1 week of new clinical symptoms or imaging abnormalities were used to calculate NLR and PLR. These ratios were compared with those of 100 healthy controls. Results: A total of 79 NMOSD patients, 75 MS patients, and 100 healthy controls were included. The mean age of NMOSD patients was significantly higher than that of MS patients ( Conclusion: NLR may serve as a useful auxiliary tool for differentiating acute attacks or relapses of NMOSD from MS and is associated with prognosis in both NMOSD and MS patients.
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