ArticleFrontiers in neurology2025
Preserved ictal responsiveness in right mesial temporal lobe epilepsy: metabolic correlates in posterior temporal networks with FDG-PET.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Automatisms with preserved responsiveness (APR) represent a distinctive clinical feature in right mesial temporal lobe epilepsy (MTLE). This study aimed to investigate whether interictal FDG-PET hypometabolism correlates with impaired responsiveness during seizures. Methods: We retrospectively analyzed 49 patients with right MTLE who underwent presurgical evaluation. Patients were stratified into APR+ ( Results: APR- patients exhibited significantly greater hypometabolism in the posterior lateral temporal cortex ( Conclusion: Consciousness impairment in right MTLE is specifically associated with posterior lateral temporal dysfunction, with broader posterior temporal vulnerability suggested by subthreshold trends. These findings identify posterior lateral temporal hypometabolism as a potential biomarker of impaired responsiveness in right MTLE and highlight the value of FDG-PET for characterizing consciousness-related network dysfunction.
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