Evidence map›Paper›PMID 41211255›Full record

ReviewCureus2025

Artificial Intelligence Across the Prostate Cancer Pathway: Screening, Imaging, Pathology, and Biomarkers.

Muhammad Rakib Hasan, Nazeer Ibraheem, Mohammad Ekhlasur Rahman, Rezuana Tamanna

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Rakib HasanUrology, Watford General Hospital, West Hertfordshire Hospitals NHS Foundation Trust, Watford, GBR.
Nazeer IbraheemUrology, The Royal Wolverhampton NHS Trust New Cross Hospital, Wolverhampton, GBR.
Mohammad Ekhlasur RahmanUrology, Watford General Hospital, West Hertfordshire Hospitals NHS Foundation Trust, Watford, GBR.
Rezuana TamannaGeneral Surgery, Craigavon Area Hospital, Northern Ireland Medical & Dental Training Agency (NIMDTA), Portadown, IRL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) has made great changes to prostate cancer screening and early detection across biomarkers, imaging, and pathology. On micro-ultrasound (micro-US), AI improves discrimination and raises specificity at comparable sensitivity versus clinical models, while multimodal magnetic resonance imaging-transrectal US (MRI-TRUS) AI achieves higher specificity at matched sensitivity. Liquid-biopsy programs combine fragmentomics with ctDNA and cell-free mRNA interpreted by AI, enabling noninvasive risk stratification and clinical feasibility. In imaging, AI for MRI matches or exceeds expert radiologists in large reader studies and MRI benchmarks; commercial tools show robust patient- and lesion-level performance. Quantitative pipelines (e.g., automated tissue-composition metrics) aid equivocal Prostate Imaging-Reporting and Data System (PI-RADS 3) lesions with PSA density, and AI-derived intraprostatic tumor volume offers independent prognostic value. Multimodal fusion of MRI with TRUS boosts detection, and automated prostate-specific membrane antigen (PSMA) PET/CT algorithms quantify tumor burden and support longitudinal response tracking. In pathology, clinical-grade AI automates cancer detection and Gleason grading, cutting reading time, ancillary tests, and second-opinion requests, while supporting integrative prognostic models. Downstream, AI accelerates radiotherapy planning, guides focal therapies and surgical margins, personalizes systemic therapy, and enables early post-treatment monitoring. Translation still requires rigorous, prospective, multi-site validation.

Indexed as

aiartificial intelligenceprostate cancerprostate imagingscreening

Identifiers

PMID41211255
PMCPMC12591259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.