ArticleAPL bioengineering2025
Digital light processing of hydrogel molds to guide cell mechanosensing and the fabrication of meniscal tissue constructs.
Article in APL bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Elastic scaffolds reinforced stem cell-laden collagen-derived hybrid hydrogels to engineer 3D anisotropic cellular microenvironment.Materials today. Bio · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The organization of cells and extracellular matrix (ECM) informs tissue function. This structure/function relationship is especially evident in musculoskeletal (MSK) tissues in which a specific ECM organization (e.g., anisotropy) guides directional properties under load. Injury disrupts the ECM structure, and new methods are needed to recapitulate the organization of cells and ECM within MSK tissue constructs to improve tissue models as well as to fabricate implants for repair. To address this, we use digital light processing (DLP) to rapidly 3D print custom molds that support large (centimeter-scale) meniscal tissue construct formation from meniscal fibrochondrocytes embedded within collagen gels. Importantly, these hydrogel molds include multiple pillars designed to anchor the tissue constructs and provide biophysical cues to direct tissue organization. Here, the effect of pillar spacing aspect ratio, mold size, and mold curvature on tissue contraction and cellular organization is investigated both experimentally and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.