Evidence map›Paper›PMID 41211042›Full record

ArticleThe Pan African medical journal2025

Advancing vaccine manufacturing in Africa: a new era for immunisation programmes towards self-sufficiency.

Frankline Sevidzem Wirsiy, Roseline Dzekem Dine, Clovis Nchinjoh Sangwe, Nancy B Tahmo, Eugene Vernyuy Yeika, Clinton Njakoi Kwemu, Jean-Claude Kindzeka Wirsiy, Denis Ebot Ako-Arrey

Abstract read
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Frankline Sevidzem WirsiyAfrica Centres for Disease Control and Prevention (Africa CDC), Addis Ababa, Ethiopia.
Roseline Dzekem DineDepartment of Social Sciences and Community Engagement, Rinda Ubuzima, Kigali, Rwanda.
Clovis Nchinjoh SangweGavi, the Vaccine Alliance, Geneva, Switzerland.
Nancy B TahmoDivision of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Eugene Vernyuy YeikaHealth Systems and Programme Manager, Ministry of Public Health, Yaounde, Cameroon.
Clinton Njakoi KwemuCameroon Baptist Convention Health Board (CBCHB), Yaoundé, Cameroon.
Jean-Claude Kindzeka WirsiyBiomedical Sciences and Health Program, Faculty of Interdisciplinary at Saint John, University of New Brunswick, New Brunswick, Canada.
Denis Ebot Ako-ArreyCatholic Relief Services (CRS), Brazzaville, Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite Africa's impressive vaccination coverage gains over the previous half-century, the continent's reliance on imported vaccines revealed significant weaknesses in disease control, especially during the COVID-19 pandemic. Establishing a strong and long-lasting vaccine manufacturing infrastructure throughout the continent is essential to achieving health sovereignty and security. The prospects, difficulties, and tactical measures needed to improve vaccine manufacturing in Africa are highlighted in this commentary. Investing in capacity building to create industrial clusters, bolstering regulatory frameworks, and utilizing public-private partnerships are important components. The Partnerships for African Vaccine Manufacturing (PAVM), spearheaded by Africa CDC and the World Health Organization (WHO) support offer blueprints for progress as well as guidelines for advancement. Improving immunisation programmes and getting ready for future public health emergencies depend heavily on achieving vaccine self-sufficiency.

Indexed as

COVID-19Immunization ProgramsVaccinesAfricaCapacity BuildingHumansPublic HealthPublic-Private Sector PartnershipsWorld Health OrganizationVaccinesAfricaimmunisation programmesVaccine manufacturing

Identifiers

PMID41211042
PMCPMC12595559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.