Evidence map›Paper›PMID 41210995›Full record

ArticleiScience2025

CHD7 regulates cardiac neural crest cell differentiation through SOX5-mediated self-activation.

Shun Yan, Andrey Bombin, Weiwei Liu, Yeimy Gonzalez-Giraldo, Feng Zhou, Huidong Shi, Qin Wang, Kai Jiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Role of CHD chromatin remodelers in heart development.World journal of pediatrics : WJP · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shun YanCenter for Biotechnology and Genomic Medicine, Augusta, GA 30912, USA.
Andrey BombinDepartment of Neuroscience and Regenerative Medicine, Augusta, GA 30912, USA.
Weiwei LiuCenter for Biotechnology and Genomic Medicine, Augusta, GA 30912, USA.
Yeimy Gonzalez-GiraldoDepartment of Neuroscience and Regenerative Medicine, Augusta, GA 30912, USA.
Feng ZhouDepartment of Neuroscience and Regenerative Medicine, Augusta, GA 30912, USA.
Huidong ShiGeorgia Cancer Center, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.
Qin WangDepartment of Neuroscience and Regenerative Medicine, Augusta, GA 30912, USA.
Kai JiaoCenter for Biotechnology and Genomic Medicine, Augusta, GA 30912, USA.

Funding

The Roles of Semaphorin Signaling During Valvuloseptal DevelopmentR01HL095783 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JIAO, KAI · 2010 to 2021
$3.4M
Epigenetic regulation of the metabolic shift in mammalian perinatal heartsR01HL167945 · NHLBI · AUGUSTA UNIVERSITY · PI KAI JIAO · 2024 to 2026
$1.8M
NHLBI NIH HHS R01 HL095783NHLBI NIH HHS R01 HL167945
6 · The paper itself

Abstract

CHARGE (coloboma of the eye, heart defects, atresia of the choanae, retardation of growth and development, genital abnormalities, and ear anomalies) syndrome, primarily caused by

Indexed as

biological sciencescellular neurosciencemolecular neuroscienceneuroscience

Identifiers

PMID41210995
PMCPMC12595127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.