Evidence map›Paper›PMID 41210930›Full record

ArticleJournal of bone and joint infection2025

Prevalence, microbiological features, and risk factors for periprosthetic joint infections in oncologic patients following tumor resection and megaprosthetic reconstruction.

Andreas G Tsantes, Dimitrios V Papadopoulos, Stavros Goumenos, Eleni Petrou, Ioannis G Trikoupis, Anastasios Roustemis, Alexandra Mpakosi, Petros Ioannou, Christos Koutserimpas, Panayiotis Gavriil and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bone and joint infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andreas G TsantesLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0002-3695-0759
Dimitrios V PapadopoulosSecond Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Stavros GoumenosFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Eleni PetrouLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Ioannis G TrikoupisFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Anastasios RoustemisFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Alexandra MpakosiDepartment of Microbiology, General Hospital of Nikaia "Agios Panteleimon", 18454 Piraeus, Greece.
Petros IoannouDepartment of Internal Medicine & Infectious Diseases, University General Hospital of Heraklion, Heraklion, Greece.
Christos KoutserimpasOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix Rousse Hospital, Hospices Civils de Lyon, Lyon North University Hospital, Lyon, France.
Panayiotis GavriilFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Daniele PiovaniDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Stefanos BonovasDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Panayiotis J PapagelopoulosFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Athanasios TsakrisDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Argirios E TsantesLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periprosthetic joint infection (PJI) after tumor resection and megaprosthetic reconstruction of bone defects is a common complication. The purpose of this study was to evaluate the prevalence of these infections, assess their microbiological profile, and identify perioperative risk factors for these complications. A single-center retrospective cohort study was conducted including 273 patients, who had undergone musculoskeletal tumor resection and megaprosthetic reconstruction. The medical records of these patients were screened for several parameters, including development of postoperative PJI. All reviewed parameters were compared between patients who developed infections and those who did not. Infection developed in 36 patients, indicating an incidence of 13.2 % (95 % confidence interval (CI): 9.4 %-17.8 %). The most common isolated pathogens in patients with PJI included coagulase-negative staphylococci (

Identifiers

PMID41210930
PMCPMC12590581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.