Evidence map›Paper›PMID 41210889›Full record

ArticleFrontiers in neuroanatomy2025

Spinal cord morphology and PKD2L1

Lugdivine Leblond, Jorge Ramirez-Franco, Caroline Michelle, Nicolas Wanaverbecq, Morgane Evin

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lugdivine LeblondAix Marseille Univ, Univ Gustave Eiffel, LBA, Marseille, France.
Jorge Ramirez-FrancoAix Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.
Caroline MichelleAix Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.
Nicolas WanaverbecqAix Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.
Morgane EvinAix Marseille Univ, Univ Gustave Eiffel, LBA, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Morphometrical studies of the mouse spinal cord are often limited to one age or sex, restricting our understanding of anatomical variability. This study provides a detailed analysis of the spinal cord in mice, examining the effects of age, sex, and spinal region, along with the distribution of PKD2L1-positive (PKD2L1 Methods: Using 811 transverse sections from a total of 18 3- and 8-week-old mice, DAPI immunofluorescence and confocal imaging, 14 dimensions of gray matter (GM), white matter (WM), and the central canal (CC) were assessed using landmarks positioning and segmentation methods. Results: Age was the most influential factor: between 3- and 8- weeks-old, the spinal cord showed reduced rostro-caudal length ( Discussion: These results indicate progressive structural changes during development, including reorganization of cells and CC architecture stabilization. The distribution of PKD2L1 Conclusion: This work provides detailed, segment-specific anatomical data crucial for developing accurate and physiological numerical models. Adding age and sex differences emphasizes the need to reflect biological variability in simulations. Additionally, the mapping of PKD2L1

Indexed as

central canalconfocal imagingmorphometrymouse modelspinal cord

Identifiers

PMID41210889
PMCPMC12592075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.