Evidence map›Paper›PMID 41210887›Full record

ArticleBiological psychiatry global open science2026

Adolescent Risky Alcohol Use Is Associated With Electrophysiological Markers of Error Processing: Findings From a Large Cohort Study.

Olga D Boer, Hanan El Marroun, Doga Ultanir, Ingmar H A Franken

Abstract read
In one paragraph

Article in Biological psychiatry global open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olga D BoerCenter for Substance Use and Addiction Research, Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Science, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Hanan El MarrounCenter for Substance Use and Addiction Research, Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Science, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Doga UltanirCenter for Substance Use and Addiction Research, Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Science, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Ingmar H A FrankenCenter for Substance Use and Addiction Research, Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Science, Erasmus University Rotterdam, Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Altered electrophysiological error processing, measured via the error-related negativity (ERN), error-related positivity (Pe), and midfrontal theta power (FM-theta), has been associated with problematic alcohol use and alcohol dependence in clinical populations. However, large-scale studies focusing on adolescent use in the general population are scarce. Moreover, the extent to which potential confounding factors shape the relationship between brain activity and alcohol use remains unclear. Methods: In the current study, we examined the relationship between adolescent alcohol use and electrophysiological markers of error processing (ERN, Pe, and FM-theta) in a large adolescent sample drawn from a population-based cohort ( Results: Linear regression analyses showed that smaller absolute ERN amplitude (indicating reduced implicit error processing) was associated with risk factors for alcohol use disorder, including early alcohol use initiation and higher binge drinking frequency. Surprisingly, higher binge drinking frequency was also associated with larger Pe amplitude. These findings remained present after adjustment for confounding variables and were not moderated by sex. Conclusions: These findings show an important link between prevalent alcohol use behaviors and altered electrophysiological markers of error processing, representing a promising step forward in using large-scale electroencephalography for brain-alcohol use research and its clinical implications.

Indexed as

AdolescenceAlcohol useEEGERPError processingTime-frequency

Identifiers

PMID41210887
PMCPMC12593575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.