Evidence map›Paper›PMID 41210859›Full record

ArticleFrontiers in medicine2025

Association between coexisting physical, cognitive, and social frailty and sarcopenia in patients undergoing maintenance hemodialysis.

Luchen Chen, Yanyu Fang, Yongze Dong, Mengjiao Zhao, Shiyan Yao, Qi Zhong, Liying Wang, Haixin Song, Guannan Ma, Huajuan Shen

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Association Between Frailty and Cognitive Impairment in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luchen ChenCollege of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Yanyu FangCollege of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Yongze DongDepartment of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou, China.
Mengjiao ZhaoCollege of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Shiyan YaoSchool of Public Health and Nursing, Hangzhou Normal University, Hangzhou, China.
Qi ZhongDepartment of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou, China.
Liying WangDepartment of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou, China.
Haixin SongCollege of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Guannan MaSchool of Public Health and Nursing, Hangzhou Normal University, Hangzhou, China.
Huajuan ShenDepartment of Nursing, Zhejiang Provincial People's Hospital, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the influencing factors of coexisting physical, cognitive, and social frailty in MHD patients and explore its association with sarcopenia, in order to provide a reference for developing comprehensive intervention strategies targeting multidimensional frailty. Methods: A convenience sample of MHD patients receiving treatment at the hemodialysis centers of two general hospitals in Hangzhou from July to August 2025 was enrolled. Data were collected using a general information questionnaire, Fried Frailty Phenotype Scale, Social Frailty Scale, Mini-Mental State Examination (MMSE), Modified Quantitative Subjective Global Assessment (MQSGA), Self-Rating Depression Scale (SDS), Social Support Rating Scale (SSRS), and International Physical Activity Questionnaire-Short Form (IPAQ-SF). Pearson correlation analysis and binary logistic regression were used to examine the co-occurrence of physical, cognitive, and social frailty and its association with sarcopenia. Results: A total of 336 questionnaires were distributed and 325 valid responses were collected. Among the 325 MHD patients, the proportions of individuals with frailty in 0, 1, 2, and 3 domains were 60.0% ( Conclusion: Approximately 11.1% of MHD patients experience coexisting physical, cognitive, and social frailty. Sarcopenia is significantly associated with this multidimensional frailty. Early identification and intervention targeting sarcopenia and its related factors may help prevent or mitigate frailty in MHD patients.

Indexed as

correlationfrailtyinfluencing factors analysismaintenance hemodialysissarcopenia

Identifiers

PMID41210859
PMCPMC12588990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.