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ArticleFrontiers in medicine2025

QBrainNet: harnessing enhanced quantum intelligence for advanced brain stroke prediction from medical imaging.

M Priyadharshini, V Murugesh, T R Mahesh, Eid Albalawi, Oumaima Saidani, Ali Algarni

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

M PriyadharshiniDepartment of Computer Science & Engineering, Faculty of Science and Technology (IcfaiTech), ICFAI Foundation for Higher Education, Hyderabad, India.
V MurugeshSchool of Computer Science, Coventry University Kazakhstan, Astana, Kazakhstan.
T R MaheshDepartment of Computer Science and Engineering, Faculty of Engineering and Technology, JAIN (Deemed-to-be University), Bengaluru, India.
Eid AlbalawiDepartment of Computer Science, College of Computer Science and Information Technology, King Faisal University, Al Ahsa, Saudi Arabia.
Oumaima SaidaniDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Ali AlgarniDepartment of Informatics and Computer Systems, College of Computer Science, King Khalid University, Abha, Asir, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Brain stroke is still one of the leading causes of death and long-term disability in the world. Early and correct diagnosis is therefore important for patient outcome. Although Convolution Neural Network (CNN), classical machine learning models, have achieved great progress in medical image classification, they have to face the performance saturation problem when dealing with high-dimensional and complex data such as medical images. To tackle these limitations, we propose QBrainNet, a quantum enhanced model, which is to enhance brain stroke prediction from medical imaging datasets. Methods: The model consists of Quantum Neural Networks (QNNs) applied as learning complex patterns in terms of medical images and Variational Quantum Circuits (VQCs) that will be used to optimize the classification. The feature extraction featured in the QNNs utilises quantum properties of superposition and entanglement to extract non-linear high-dimensional patterns in images related to stroke that may not be captured using classical limits. The VQCs, in turn, are applied to optimize the model performance, further allocating the boundaries of the decision and enhancing the model performance in terms of accuracy by optimizing the quantum gates and operators used during the work. QBrainNet utilizes the combination of such quantum properties as entanglement and superposition to represent more complicated non-linear patterns in stroke-specific images in a better manner than a classical application does. Results: This paper proposes a hybrid classical-quantum scheme: preprocessing classically, and learning quantum-enhanced. Quantum gates and operators are used when performing the quantum phase to optimize decision boundaries, achieving vastly enhanced prediction accuracy and efficiency performance. Experimental results indicate that QBrainNet has a better accuracy (96%) and AUC-PR (0.97) than the classical models like CNN, SVM, and Random Forest, proving the superior performance of QBrainNet in stroke detection. Discussion: The inference time is shorter, so the model can be used as a real-time clinical application. This article points to the possibilities quantum computing can have in revolutionizing medical diagnostics, especially stroke prediction.

Indexed as

brain stroke predictionearly stroke detectionmedical imagingquantum computingquantum intelligencequantum neural networks (QNN)

Identifiers

PMID41210857
PMCPMC12589079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.