Evidence map›Paper›PMID 41210753›Full record

ArticleACS omega2025

A Two-Stage Method for Purifying Alpha-Mangostin: Sequential Solvent Extraction and Preparative Liquid Chromatography.

Amaraporn Kaewchada, Apivich Phumjaroen, Preuk Tangpromphan, Attasak Jaree

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amaraporn KaewchadaDepartment of Agro-industrial, Food, and Environmental Technology, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok, Bang Sue, Bangkok 10800, Thailand.
Apivich PhumjaroenCenter for High-Value Products from Bioresources: HVPB. Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok 10900, Thailand.
Preuk TangpromphanCenter for High-Value Products from Bioresources: HVPB. Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok 10900, Thailand.
Attasak JareeCenter for High-Value Products from Bioresources: HVPB. Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok 10900, Thailand.ORCID https://orcid.org/0000-0002-7751-4494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research aimed to establish the optimal conditions for the purification of alpha-mangostin from mangosteen pericarp, employing a two-stage process involving solvent extraction and liquid chromatography. Initially, a sequential solvent extraction protocol, utilizing deionized water and hexane, was implemented to effectively remove both polar and nonpolar impurities. Subsequently, alpha-mangostin was extracted using acetonitrile, and the solvent was removed through evaporation and precipitation, yielding a xanthone-rich fraction. This fraction was then subjected to quantitative liquid chromatography, wherein the influence of mobile phase flow rate, mobile phase composition, feed concentration, and column temperature on purification efficiency was systematically evaluated. The optimized purification parameters, namely a mobile phase flow rate of 4 mL/min, a mobile phase composition of 80% acetonitrile and 20% deionized water, a feed concentration of 3 mg/mL, and a column temperature of 35 °C, resulted in alpha-mangostin with a purity of 83.33%.

Identifiers

PMID41210753
PMCPMC12593079

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.