Evidence map›Paper›PMID 41210718›Full record

ArticleFrontiers in plant science2025

Study on mechanism of temperature-modulated polyphenolic biosynthesis in cigar tobacco leaves.

Jiahao Kang, Bo Fu, Xiaoxiao Yan, Menglan Xiao, Weili Yang, Mingqin Zhao

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahao KangCollege of Tobacco Science, Flavors and Fragrance Engineering & Technology Research Center of Henan Province, Henan Agricultural University, Zhengzhou, China.
Bo FuCollege of Tobacco Science, Flavors and Fragrance Engineering & Technology Research Center of Henan Province, Henan Agricultural University, Zhengzhou, China.
Xiaoxiao YanCollege of Tobacco Science, Flavors and Fragrance Engineering & Technology Research Center of Henan Province, Henan Agricultural University, Zhengzhou, China.
Menglan XiaoCollege of Tobacco Science, Flavors and Fragrance Engineering & Technology Research Center of Henan Province, Henan Agricultural University, Zhengzhou, China.
Weili YangSichuan Provincial Branch of China National Tobacco Corporation, Dazhou, China.
Mingqin ZhaoCollege of Tobacco Science, Flavors and Fragrance Engineering & Technology Research Center of Henan Province, Henan Agricultural University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigars as an economic crop, inappropriate growth temperature can detrimentally affect cigar quality, yet our knowledge about the response of cigar tobacco leaves (CTLs) to such stressors remains limited. We subjected CTLs to prolonged mild low-temperature and high-temperature treatments and systematically assessed oxidative stress markers, antioxidant enzyme activities, phenolic and flavonoid accumulation, and transcriptomic dynamics. Weighted gene co-expression network analysis (WGCNA) and correlation-based approaches were used to identify key genes and regulators.This study revealed that both long-term mild low and high temperatures in CTLs triggered excessive production of reactive oxygen species (ROS) and disrupted antioxidant enzyme systems. Exposure to low temperatures resulted in increased accumulation of phenolic and flavonoids, while high temperatures were associated with either negative or negligible effects on these metabolites. Moreover, low temperatures significantly stimulated phenylpropanoid biosynthesis, in contrast to the negative effects observed at high temperatures. Correlation analysis indicated that

Indexed as

cigar tobaccolong-termPhenylpropanoid biosynthesisRNA-seqtemperature stressWGCNA

Identifiers

PMID41210718
PMCPMC12589083

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.