Evidence map›Paper›PMID 41210702›Full record

ArticleFrontiers in plant science2025

The dynamic epigenetic atlas and its effects on instability of starch and seed storage protein quality traits in wheat (

Yaping Wang, Lingfeng Miao, Haibin Wu, Xiaoliang Duan, Liu Chang, Yu Hong, Weilong Guo, Hui Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yaping WangGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.
Lingfeng MiaoFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization, Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, China.
Haibin WuGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.
Xiaoliang DuanGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.
Liu ChangGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.
Yu HongGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.
Weilong GuoFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization, Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, China.
Hui SunGrain Quality and Nutrition Research Institute, Academy of National Food and Strategic Reserves Administration, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental factors significantly influence wheat grain quality by modulating starch biosynthesis and seed storage protein (SSP) composition, yet the underlying epigenetic mechanisms remain elusive. Here, we performed an integrated multi-omics analysis on the wheat cultivar 'Fengdecunmai 5' cultivated in two contrasting environments using WGBS, ChIP-seq (H3K27ac/H3K27me3), and RNA-seq. Epigenomic profiling revealed that environmental variation triggers extensive epigenetic reprogramming, with changes in H3K27ac enrichment being a primary epigenetic signature associated with the transcriptional divergence of starch and SSP biosynthesis genes during early development. Reconstruction of the transcriptional regulatory networks (TRNs) identified 86 essential transcription factors (TFs) that regulate 9,250 target genes in response to environmental impact. Our findings provide novel insights into the molecular basis of wheat quality instability across environments from an epigenetic perspective and highlight the critical role of histone modifications in regulating wheat seed quality.

Indexed as

DNA methylationhistone modificationSSPstarchwheat

Identifiers

PMID41210702
PMCPMC12592202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.