Evidence map›Paper›PMID 41210595›Full record

ArticlePhysics and imaging in radiation oncology2025

Time-saving potential of daily online adaptive proton therapy for head and neck cancers by reducing number of beams.

Evangelia Choulilitsa, Katarzyna Czerska, Barbara Bachtiary, Damien Charles Weber, Antony John Lomax, Francesca Albertini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Evangelia ChoulilitsaCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Katarzyna CzerskaCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Barbara BachtiaryCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Damien Charles WeberCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Antony John LomaxCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Francesca AlbertiniCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Standard care for head and neck cancer (HNC) treatment with proton therapy typically involves a 4-6 field Intensity Modulated Proton Therapy plan to enhance robustness towards anatomical changes and patient misalignments. This study aimed to evaluate whether a more efficient plan with fewer beams, designed for faster delivery, can be combined with online daily adaptation (DAPT) to provide treatment of comparable quality, and improve treatment outcomes. Materials and methods: We retrospectively analyzed five HNC patients with available daily 3D imaging treated at our institution. To simulate DAPT, synthetic Computed Tomography (CT) images were generated by deforming planning CT to each daily Cone-Beam CT with targets and organs-at-risk (OARs) propagated to daily images. Three plans were created per-patient: Offline Results: Offline Conclusions: Our delivery efficiency study shows that DAPT can allow fewer beams to achieve faster delivery, as shown in case of DAPT

Indexed as

Fast deliveryHead and neck cancerOnline adaptive proton therapyReduced beam configuration

Identifiers

PMID41210595
PMCPMC12593431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.