Evidence map›Paper›PMID 41210553›Full record

ArticleJournal of biomedical optics2025

Development of a dynamic pulsatile phantom for the photoplethysmographic waveform at the radial artery.

Tananant Boonya-Ananta, Andres J Rodriguez, Ajmal Ajmal, Amanda N Sanchez, JunZhu Pei, Ernesto Rodriguez, Abiel Vasallo Veliz, Christian Suastegui, Nicole Paz, Jessica C Ramella-Roman

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tananant Boonya-AnantaFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.ORCID https://orcid.org/0009-0003-3589-6249
Andres J RodriguezFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.ORCID https://orcid.org/0000-0002-2159-8123
Ajmal AjmalFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.ORCID https://orcid.org/0009-0000-4600-0602
Amanda N SanchezFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.
JunZhu PeiFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.
Ernesto RodriguezFlorida International University, Department of Mechanical Engineering, Miami, Florida, United States.
Abiel Vasallo VelizFlorida International University, Department of Mechanical Engineering, Miami, Florida, United States.ORCID https://orcid.org/0009-0005-0387-6352
Christian SuasteguiFlorida State University, Department of Chemical and Biomedical Engineering, Tallahassee, Florida, United States.
Nicole PazUniversity of Miami, Department of Mechanical and Aerospace Engineering, Coral Gables, Florida, United States.
Jessica C Ramella-RomanFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.ORCID https://orcid.org/0000-0002-5710-6004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Cardiovascular disease remains one of the leading causes of death in the United States. Wearable optical systems are known to have errors and biases for individuals with different skin tones as well as different levels of obesity. By enabling the development and validation of wearable technologies across diverse populations, we advance equitable healthcare solutions and foster the creation of more reliable, personalized health monitoring systems. Aim: We aim to develop a dynamic wrist phantom replicating the radial artery pulse, addressing physiological variations such as skin tone and obesity that impact wearable health technologies. Approach: A silicone-based phantom mimics human tissues' mechanical and optical properties. A cam-driven pulsatile flow system simulated physiological blood flow, with key waveform features controlled by mechanical components. Optical properties were adjusted using titanium dioxide and carbon black to match Fitzpatrick skin tones I to VI, whereas radial artery depth variations simulated the effects of obesity. The phantom system incorporated a blood-mimicking fluid to replicate the optical absorption characteristics of whole blood. Results: The phantom successfully replicated photoplethysmography (PPG) waveforms at heart rates ranging from 59 to 118 beats per minute, demonstrating physiologically representative features such as systolic and diastolic peaks. Signal degradation was observed with increasing vessel depth and darker skin tones, consistent with real-world challenges in wearable device accuracy. The alternating signal/baseline signal ratio of the PPG signal decreased by up to 77.8% for darker skin tones and deeper vessels. The phantom also validated its performance against commercial wearables, supporting its utility in device testing. Conclusions: This dynamic wrist phantom provides a robust platform for evaluating optical devices under controlled and representative conditions, addressing critical gaps in inclusivity and accuracy.

Indexed as

Phantoms, ImagingPhotoplethysmographyPulsatile FlowRadial ArteryEquipment DesignHumansWearable Electronic DevicesWristdynamic phantomphotoplethysmographywearables

Identifiers

PMID41210553
PMCPMC12593935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.