Evidence map›Paper›PMID 41210492›Full record

ArticleJournal of ophthalmic & vision research2025

Efficacy of a Ceftazidime-loaded Nanofiber Insert in Treating

Shahla Mirzaeei, Mojtaba Eidizadeh, Abbas Khosravi, Masood Bagheri, Shiva Taghe

Abstract read
In one paragraph

Article in Journal of ophthalmic & vision research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shahla MirzaeeiPharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mojtaba EidizadehClinical Research Development Center, Imam Khomeini and Mohammad Kermanshahi and Farabi Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Abbas KhosraviClinical Research Development Center, Imam Khomeini and Mohammad Kermanshahi and Farabi Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Masood BagheriClinical Research Development Center, Imam Khomeini and Mohammad Kermanshahi and Farabi Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Shiva TaghePharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to determine the efficacy of ceftazidime-containing nanofibers in treating corneal ulcers induced by the bacterium Methods: This animal-assisted intervention involved 12 adult male New Zealand rabbits, each weighing between 3.5 and 4 kg. The animals were randomly assigned to two groups of six: an intervention group that received a ceftazidime nanofiber insert treatment and a control group that received no treatment. In the intervention group, the right eye was used as a test sample for ulcer induction and ceftazidime-loaded nanofiber examination, while the left eye served as a control to observe any inflammatory or irritating symptoms caused by the nanofiber in the absence of the active pharmaceutical compound. Examinations were performed daily, with slit lamp images taken on days 2, 4, 6, 9, 12, and 15. Clinical responses were recorded and graded according to a clinical examination table. Results: Prior to the intervention, both groups exhibited a similar severity of corneal ulcers. After 48 hours, four of the six rabbits in the intervention group were positive for Conclusion: Given the observed effectiveness of the developed nanofiber in treating corneal ulcers induced by

Indexed as

Animal ModelCeftazidimeCorneal UlcerDrug DeliveryNanofiber Insert

Identifiers

PMID41210492
PMCPMC12590448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.