ArticleAME case reports2025
Postoperative adrenal cortical insufficiency following adrenal adenoma removal: a case report.
Article in AME case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The adrenal gland is one of the important endocrine organs in the human body. With advancements in medical technology, the diagnosis rates of adrenal diseases, such as adrenal tumors and adrenal cortical hyperplasia, have been steadily increasing. Surgical intervention is the mainstream method for treating adrenal tumors; however, unilateral complete adrenalectomy may impair the patient's adrenal cortical function, leading to adrenal insufficiency (AI). AI is caused by a deficiency of glucocorticoids, which may be accompanied or not accompanied by reductions in mineralocorticoids and sex hormones. The clinical manifestations can be prolonged and nonspecific, sometimes resulting in misdiagnosis and mistreatment. Adrenal venous sampling (AVS) is typically one of the diagnostic methods used to determine the presence of a functioning adrenal adenoma. After unilateral adrenalectomy for a functioning adrenal adenoma, AI may occur. Here, we summarize a case of a patient with a functioning adrenal adenoma who developed AI following unilateral adrenalectomy. Case Description: Here, we report a case of AI following unilateral adrenalectomy. The patient is a 28-year-old woman with a 2-year history of hypertension and a right adrenal mass that had been detected for more than 3 months. An abdominal computed tomography (CT) scan suggested a mass in the right adrenal gland. Preoperative AVS indicated elevated levels of aldosterone and cortisol in the right adrenal vein. After thorough preoperative preparations, a laparoscopic right adrenalectomy was performed, and postoperative pathology confirmed an adrenal adenoma. After discharge, the patient experienced recurrent symptoms of nausea and vomiting. Upon returning to the hospital, blood tests revealed abnormally low levels of cortisol in the peripheral blood, suggesting AI. After receiving glucocorticoid treatment, her symptoms improved. Conclusions: Primary AI is relatively rare in clinical practice, typically occurring after unilateral adrenal surgery. The clinical manifestations are nonspecific, which often leads to misdiagnosis and mistreatment. Preoperative AVS for hormone level assessment can assist in diagnosing the nature of a functioning adrenal adenoma and help prevent postoperative AI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.