Granular cell tumor of the chest wall: the first case report and literature review.

Background: Granular cell tumor (GCT) is an exceedingly rare lesion primarily characterized by benign hyperplasia. GCT was first described by Professor Abrikossoff in 1926 in the tongue, and has since been identified in various anatomical locations. GCT of the chest wall is particularly uncommon, with limited documentation in literature. Case Description: A 32-year-old female presented with a right anterior chest wall tumor persisting for over 4 years. Examination revealed a localized bulge near the sternal manubrium, with normal overlying skin. Palpation revealed a firm mass. Chest computed tomography (CT) scan indicated that the tumor size was approximately 2.5 cm × 2.5 cm × 1.5 cm, with distinct boundaries and limited mobility. The chest wall mass was excised under general anesthesia. The tumor was completely excised with an electric knife and submitted for pathological analysis. Pathological analysis confirmed a granulosa cell tumor of the chest wall. Routine anti-inflammatory treatment and wound compression bandaging were administered, with discharge occurring one week later. Three years post-resection, there was no evidence of recurrence nor metastasis. Conclusions: GCT lacks distinct imaging features, with diagnosis primarily dependent on pathological examination. Typically, these tumors are found in the subcutaneous or submucosal layers. Complete surgical resection is the preferred treatment for GCT. The prognosis for benign granulocytoma post-resection is favorable, with a low recurrence rate. Postoperative follow-up is essential.