ReviewAsia-Pacific journal of oncology nursing2025
Negative pressure wound therapy for preventing wound complications following stoma reversal: A systematic review and meta-analysis of randomized controlled trials.
Review in Asia-Pacific journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the effectiveness of negative pressure wound therapy in preventing wound complications following colorectal stoma reversal and provide evidence-based recommendations for its clinical application. Methods: A comprehensive search was conducted across five English databases (PubMed, Embase, Web of Science, Cochrane Library, Scopus) and three Chinese databases (Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang) from their inception to December 2024. Grey literature and trial registries were also included. Eligible studies were randomized controlled trials investigating negative pressure wound therapy for patients undergoing stoma reversal. Primary outcomes included wound complications (surgical site infections, hematoma, seroma); secondary outcomes comprised hospital stay, wound healing duration, and dressing costs. Results: Eight randomized trials involving 517 patients were included. Negative pressure wound therapy significantly reduced wound complications (odds ratio, 0.50; 95% confidence interval, 0.27-0.94), shortened wound healing time (mean difference, -4.31; 95% confidence interval, -4.97 to -3.65), and decreased hospital stay (mean difference, -1.05; 95% confidence interval, -1.70 to -0.41). Subgroup analysis demonstrated benefits in the linear closure group (odds ratio, 0.11; 95% confidence interval, 0.02-0.49) but not in the purse-string closure groups. No significant differences were observed in surgical site infections, hematoma, seroma, or dressing costs. Conclusions: Negative pressure wound therapy reduces wound complications, accelerates wound healing, and shortens hospital stays after stoma reversal. Standardized protocols and additional high-quality trials are required to establish negative pressure wound therapy as a routine practice. Systematic review registration: Prospectively registered in PROSPERO (ID CRD42023451001).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.