Evidence map›Paper›PMID 41210227›Full record

ArticleFrontiers in pediatrics2025

Connecting research and community: a methodological framework for investigating CMV transmission in childcare settings.

Karen Del'Olio, Annie Geiger, Judith Terry, Cindi Callaghan, Lauren Howe, Cheryl Hamel, Delaney Platia, Alyssa Blake, Lisa Tran, Anne Davenport and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Karen Del'OlioInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Annie GeigerInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Judith TerryInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Cindi CallaghanAcademic Services Group, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Lauren HoweempHowered PR, LLC, Leominster, MA, United States.
Cheryl HamelInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Delaney PlatiaInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Alyssa BlakeInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Lisa TranInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Anne DavenportInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Elizabeth OrvekDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, MA, United States.
Stephen LammiInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Bruce BartonDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, MA, United States.
Timothy KowalikDepartment of Microbiology, UMass Chan Medical School, Worcester, MA, United States.
John HolikDepartment of Microbiology, UMass Chan Medical School, Worcester, MA, United States.
Anne MirzaDepartment of Microbiology, UMass Chan Medical School, Worcester, MA, United States.
Olesea CojohariDepartment of Microbiology, UMass Chan Medical School, Worcester, MA, United States.
Kelsey WoodsInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Susan DrukerInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
Syed Saad NaeemInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.
John D Diaz-DecaroModernaTX, Inc., Cambridge, MA, United States.
Madeleine HaydenModernaTX, Inc., Cambridge, MA, United States.
Iliana Leony LassoModernaTX, Inc., Cambridge, MA, United States.
Juli GulpinarModernaTX, Inc., Cambridge, MA, United States.
Sandeep BasnetModernaTX, Inc., Cambridge, MA, United States.
Lori PantherModernaTX, Inc., Cambridge, MA, United States.
Andrew NatenshonModernaTX, Inc., Cambridge, MA, United States.
Thejas SuvarnaCareEvolution, Ann Arbor, MI, United States.
Emma HarmanCareEvolution, Ann Arbor, MI, United States.
Kelley BridgesCareEvolution, Ann Arbor, MI, United States.
Summer SchraderCareEvolution, Ann Arbor, MI, United States.
Laura GibsonInfectious Disease and Immunology, Departments of Medicine and of Pediatrics, UMass Chan Medical School, Worcester, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CMV Transmission and Immune Tracking (TransmIT) Study was developed to address critical gaps in understanding of cytomegalovirus (CMV) transmission dynamics in early education and care (EEC) settings. This two-stage, community-engaged study design integrates EEC center partnerships, digital study platforms, and data pipeline infrastructures to enable longitudinal virologic and immunologic surveillance in this high-exposure environment. Stage I focused on establishing foundational components of the study, including a geographically diverse EEC center network, culturally tailored recruitment strategies, a community advisory board, protocols for participant enrollment and saliva sample collection, and optimized laboratory assays to measure viral shedding in saliva. The study approach honed during Stage I is intended to support future longitudinal investigations into viral shedding patterns, immune responses, and co-infections among children and staff in EEC centers. This manuscript presents a methodological framework for conducting community-centered scalable research in early childhood settings with relevance for CMV and other infectious diseases of public health importance.

Indexed as

CMVCMV transmissioncommunity engagementdiversityearly education and care centersequity and inclusion

Identifiers

PMID41210227
PMCPMC12589089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.