Evidence map›Paper›PMID 41210126›Full record

ArticleFrontiers in psychiatry2025

Adverse childhood experiences and their impact on primary headache patients: a cross-sectional study.

Alexander Pabón Moreno, Valentina Gonzalez Galindo, Alexandra Hurtado-Ortiz, Maricel Licht-Ardila, Edgar Fabian Manrique-Hernández, Alejandra Mendoza-Monsalve, Angelica Tatiana Pérez-Cárdenas, Ximena Jaely Forero, Andreina Judith Portilla, Federico Silva Sieger and 1 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander Pabón MorenoNeurological Institute, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Valentina Gonzalez GalindoUniversidad de Santander, Faculty of Medical Sciences and Health, School of Medicine, Neuroscience Group, Bucaramanga, Colombia.
Alexandra Hurtado-OrtizPostgraduate Department in Infectious Disease, Universidad de Santander, Bucaramanga, Colombia.
Maricel Licht-ArdilaDepartment of Epidemiology, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Edgar Fabian Manrique-HernándezDepartment of Epidemiology, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Alejandra Mendoza-MonsalveDepartment of Epidemiology, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Angelica Tatiana Pérez-CárdenasDepartment of Epidemiology, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Ximena Jaely ForeroNeurological Institute, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Andreina Judith PortillaNeurological Institute, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Federico Silva SiegerNeurological Institute, Hospital Internacional de Colombia - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.
Elkin Llanez AnayaUniversidad de Santander, Faculty of Medical Sciences and Health, School of Medicine, Neuroscience Group, Bucaramanga, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Adverse Childhood Experiences (ACEs), including abuse and household dysfunction, can have lasting effects on development and health, increasing risks for chronic diseases and mental health issues. Objective: to estimate the prevalence of ACEs in this population and to determine the factors associated with these experiences. Methods: A cross-sectional study was conducted at a Colombian high-complexity institution, including adults with primary headaches according to ICHD-3 criteria. Statistical analysis involved bivariate comparisons and multivariate logistic regression, with goodness-of-fit assessed using the Hosmer and Lemeshow test. All analyses were performed using Stata 16. Results: 138 patients with primary headaches were included, 77.54% reported experiencing some form of ACEs, with 34.06% having scores of 4 or higher. Physical abuse was the most common ACE (9.13%). Women had a higher probability of reporting ACEs (OR: 8.613, 95% CI: 1.006-73.776, p = 0.049). Those with severe disability (MIDAS score) were less likely to report severe ACEs (OR: 0.293, 95% CI: 0.096-0.899, p = 0.032). Conclusion: This study demonstrates a strong relationship between adverse childhood experiences and primary headaches, highlighting the need to incorporate childhood trauma assessment into neurological practice.

Indexed as

adverse childhood experienceschildhood traumaheadache disordersneurologyrisk factors

Identifiers

PMID41210126
PMCPMC12590181

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