ArticleInfection and drug resistance2025
Bloodstream Infections in Non-ICU Hospitalized Patients: Impact of Pathogen Group on Clinical Outcomes-A Retrospective Cohort Study From Türkiye.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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9 authors.
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Abstract
Background: Bloodstream infections (BSIs) in non-intensive care unit (ICU) wards are common yet less well characterized than ICU BSIs. Differences in monitoring intensity, diagnostic timelines, empirical therapy, and local resistance may shape outcomes, but pathogen-specific data in non-ICU settings remain limited. To address this gap, we provide regional data from Türkiye. Methods: We conducted a retrospective cohort study at a tertiary-care center in Türkiye, including 537 adult non-ICU inpatients with first monomicrobial BSI episodes between January 2020 and November 2023. Pathogens were grouped as Gram-negative, Gram-positive, or fungal. Demographic, clinical, microbiological, and outcome data were analyzed. Independent predictors of mortality were evaluated using multivariable logistic regression. Results: Among 537 patients (mean age 66.4 ± 16.4 years), Gram-negative pathogens predominated (65.0%), followed by Gram-positive (25.0%) and fungal pathogens (10.1%). The most frequent microorganisms were Conclusion: In non-ICU settings, early recognition, rapid organism identification, and tailored antimicrobial/antifungal stewardship are essential-particularly given local resistance pressures (eg, carbapenem-resistant
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