Evidence map›Paper›PMID 41210055›Full record

ArticleCureus2025

Liver Cirrhosis in Pregnancy and Its Fetal Outcomes: A Prospective Case Series.

Catherine Param Paramamanathan, Krishna Kumar, Kavitha Nagandla, Khai H Wong

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine Param ParamamanathanObstetrics and Gynecology, Tuanku Ja'afar Hospital, Seremban, MYS.
Krishna KumarObstetrics and Gynecology, Tuanku Ja'afar Hospital, Seremban, MYS.
Kavitha NagandlaObstetrics and Gynecology, IMU University, Kuala Lumpur, MYS.
Khai H WongObstetrics and Gynecology, IMU University, Kuala Lumpur, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy in women with cirrhosis is uncommon and carries substantial maternal and fetal risks, yet outcomes may improve with coordinated multidisciplinary care. We prospectively followed three pregnant women with confirmed cirrhosis between January 2023 and June 2024 in a tertiary hepatology-maternal-fetal medicine clinic. Management strategies included disease severity assessment, targeted endoscopy, beta-blockers for portal hypertension, antiviral therapy for hepatitis B, hematologic optimization, and individualized delivery planning. Two women had compensated cirrhosis without portal hypertension, and one had a history of decompensation with persistent portal hypertension. Deliveries comprised two cesarean sections, one for pathological cardiotocography and one for failed trial of labor, and one induced vaginal birth following platelet transfusion. No cases of variceal hemorrhage, hepatic encephalopathy, or maternal death occurred. All neonates were liveborn with Apgar scores of 9 at one and five minutes; one had growth restriction. At six weeks postpartum, all mothers remained clinically stable, and hepatitis B prophylaxis prevented vertical transmission. This case series highlights that multidisciplinary management enables favorable outcomes in selected cirrhotic pregnancies.

Indexed as

autoimmune hepatitischronic hepatitis bcirrhosisfetal growth restrictionportal hypertensionpregnancy

Identifiers

PMID41210055
PMCPMC12595598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.