Evidence map›Paper›PMID 41209970›Full record

ArticleCureus2025

Epidemiology of Oral Cancer in Cyprus: A Population-Based Cancer Registry Study and Policy Implications.

Chrystala Charalambous, Aristomenis Syngelakis, Maria Myrto Solomou, George Pantelas, Smaragda Diamanti

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chrystala CharalambousSchool of Dentistry, European University Cyprus, Nicosia, CYP.
Aristomenis SyngelakisSchool of Dentistry, European University Cyprus, Nicosia, CYP.
Maria Myrto SolomouSchool of Dentistry, European University Cyprus, Nicosia, CYP.
George PantelasSchool of Dentistry, European University Cyprus, Nicosia, CYP.
Smaragda DiamantiSchool of Dentistry, European University Cyprus, Nicosia, CYP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOral cancer is a major global health issue, with prognosis limited by late diagnosis and aggressive behavior. Although Cyprus has reported a low incidence historically, recent increases highlight the need for epidemiological assessment.

methodsA retrospective population-based study analyzed oral cancer cases recorded from 1998 to 2021. Cases were identified using ICD-10 codes. Demographic variables (sex, age), tumor site, and staging were examined. Crude and age-standardized incidence rates were calculated to assess trends.

resultsA total of 1,070 oral cancer cases were identified (1.4% of all cancers), with a male predominance (688 men (64.3%) and 382 women (35.7%)). Most patients were aged ≥55 years (69.8%), while 29% were <55. Incidence increased over time, especially for cancers of the tongue and oral cavity. Localized disease was the single largest category (38% overall; 46% among cases with known stage), while 6% had distant metastases. Although incidence in Cyprus is below global averages, recent trends reflect those in developed countries.

conclusionsThe rising incidence of oral cancer in Cyprus highlights the need for targeted public health strategies. Initiatives should focus on reducing risk factors, raising awareness among professionals and the public, and improving screening to enhance early detection.

Indexed as

cyprusepidemiologyhealth policyoral cancerrisk factors

Identifiers

PMID41209970
PMCPMC12592734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.