Evidence map›Paper›PMID 41209960›Full record

ReviewCureus2025

Induction of Labor: A Narrative Review for Clinical Use.

Esther Namutosi, Prosper Akankwasa, Joshua B Matokota, Daniel D Ssempanyi, John Katongole, Jackson Kakooza, Catherine Lewis, Emmanuel Okurut, Daniel U Owu, Nightingale Senaji

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Esther NamutosiDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
Prosper AkankwasaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
Joshua B MatokotaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
Daniel D SsempanyiDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
John KatongoleDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
Jackson KakoozaDepartment of Surgery, Kampala International University, Ishaka, UGA.
Catherine LewisDepartment of Surgery, St. Joseph's Hospital Kitovu, Masaka, UGA.
Emmanuel OkurutDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, UGA.
Daniel U OwuDepartment of Physiology, Kampala International University, Ishaka, UGA.
Nightingale SenajiDepartment of Obstetrics and Gynecology, Dagoretti Sub-county Hospital Mutuini, Nairobi, KEN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induction of labor (IOL) is a pivotal obstetric intervention employed when continuing pregnancy poses greater risks than delivery. Cervical readiness, defined as vaginal delivery within 24-48 hours without significant complications, is assessed via the Bishop Score or transvaginal ultrasonography (TVS). TVS is a key predictor of IOL success. Mechanical methods, such as a Foley catheter, and pharmacological agents (e.g., misoprostol and dinoprostone), facilitate cervical ripening. Indications for IOL include postterm pregnancy, hypertensive disorders, and intrauterine fetal demise, with timing tailored to maternal and fetal factors such as 39 weeks for low-risk cases and 37 weeks for mild preeclampsia. Special conditions, such as previous cesarean sections, require individualized approaches due to risks like uterine rupture, while hypertensive disorders necessitate prompt intervention to optimize outcomes. Complications such as failed induction, uterine hyperstimulation, and fetal distress underscore the need for vigilant monitoring. Despite challenges, IOL remains integral to obstetric care, enhancing maternal and neonatal safety through evidence-based practices. Future research should refine success metrics and optimize combined mechanical-pharmacological strategies to improve efficacy and reduce adverse events, ensuring a balanced risk-benefit profile across diverse clinical contexts. This narrative review synthesizes current evidence on IOL, encompassing definitions, indications, methods, clinical scenarios, complications, and outcomes, emphasizing collaborative decision-making between healthcare providers and pregnant individuals.

Indexed as

bishop scorecervical ripeningfetal outcomesinduction of labormaternal outcomesoxytocinprostaglandins

Identifiers

PMID41209960
PMCPMC12595975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.