ArticleCureus2025
Barely There But Existent: Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a 62-year-old female patient who presented to the Accident & Emergency (A&E) department with upper airway edema. Her past medical history included hypertension, obstructive sleep apnea, and ischemic heart disease. She had been previously hospitalized for a lower respiratory infection. On this occasion, she presented with upper airway swelling secondary to angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema, requiring endotracheal intubation. Initial management in the A&E department, under differential consideration for anaphylaxis and Ludwig's angina, included oxygen via a non-rebreather mask (NRM), intramuscular adrenaline, intravenous dexamethasone, nebulization with Pulmicort, and antibiotic coverage with ceftriaxone and metronidazole. Despite these measures, progressive airway edema necessitated intubation. The patient was subsequently transferred to a Level 4 hospital under the care of the maxillofacial team, managed conservatively, and maintained on ventilation until the edema resolved. Surgical intervention was deemed unnecessary. ACEI-induced angioedema is a rare but potentially life-threatening adverse effect of ACEIs, which are widely prescribed for hypertension, heart failure, and chronic kidney disease. A thorough medication history is essential for the timely recognition and management of this condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.